| Title | TREM2 and Amyloid Beta: A Love-Hate Relationship. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Udeochu J, Sayed FA, Gan L |
| Journal | Neuron |
| Volume | 97 |
| Issue | 5 |
| Pagination | 991-993 |
| Date Published | 2018 Mar 07 |
| ISSN | 1097-4199 |
| Abstract | Mutations in TREM2 increase risk for late-onset AD. In this issue of Neuron, Zhao et al. (2018) show that TREM2 binds Aβ to enhance its clearance and Lee et al. (2018) demonstrate that human TREM2 expression in AD mice ameliorates Aβ-associated deficits. |
| DOI | 10.1016/j.neuron.2018.02.018 |
| Alternate Journal | Neuron |
| PubMed ID | 29518360 |
| Grant List | K12 GM081266 / GM / NIGMS NIH HHS / United States |