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Found 19 results
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Parkinson Disease
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2023
Garcia CP
,
Licht-Murava A
,
Orr AG
. 2023.
Effects of adenosine A2A receptors on cognitive function in health and disease.
.
Int Rev Neurobiol. 170:121-154.
Gao V
,
Briano JA
,
Komer LE
,
Burré J
. 2023.
Functional and Pathological Effects of α-Synuclein on Synaptic SNARE Complexes.
.
J Mol Biol. 435(1):167714.
Lai Y
,
Zhao C
,
Tian Z
,
Wang C
,
Fan J
,
Hu X
,
Tu J
,
Li T
,
Leitz J
,
Pfuetzner RA
et al.
. 2023.
Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering.
.
Proc Natl Acad Sci U S A. 120(44):e2310174120.
Sharma M
,
Burré J
. 2023.
α-Synuclein in synaptic function and dysfunction.
.
Trends Neurosci. 46(2):153-166.
2017
Orr AL
,
Rutaganira FU
,
de Roulet D
,
Huang EJ
,
Hertz NT
,
Shokat KM
,
Nakamura K
. 2017.
Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease.
.
Neurochem Int. 109:106-116.
Pathak D
,
Berthet A
,
Bendor JT
,
Yu K
,
Sellnow RC
,
Orr AL
,
Nguyen MK
,
Edwards RH
,
Manfredsson FP
,
Nakamura K
. 2017.
Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons.
.
eNeuro. 4(2)
2015
Burré J
. 2015.
The Synaptic Function of α-Synuclein.
.
J Parkinsons Dis. 5(4):699-713.
2013
Pranski E
,
Van Sanford CD
,
Dalal N
,
Orr AL
,
Karmali D
,
Cooper DS
,
Gearing M
,
Lah JJ
,
Levey AI
,
Betarbet R
. 2013.
NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.
.
Neurosci Lett. 547:16-20.
2012
Huang Y
,
Shenoy S
,
Lu B
,
Liu W
,
Li C
. 2012.
Kinase signaling dysfunction in Parkinson's disease: a reverse genetic approach in Drosophila.
.
J Neurogenet. 26(2):158-67.
Sharma M
,
Burré J
,
Südhof TC
. 2012.
Proteasome inhibition alleviates SNARE-dependent neurodegeneration.
.
Sci Transl Med. 4(147):147ra113.
Burré J
,
Sharma M
,
Südhof TC
. 2012.
Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities.
.
J Neurosci. 32(43):15227-42.
2011
Liu W
,
Acín-Peréz R
,
Geghman KD
,
Manfredi G
,
Lu B
,
Li C
. 2011.
Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.
.
Proc Natl Acad Sci U S A. 108(31):12920-4.
Bosco DA
,
LaVoie MJ
,
Petsko GA
,
Ringe D
. 2011.
Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.
.
Cold Spring Harb Perspect Biol. 3(10):a007500.
2010
Vives-Bauza C
,
Zhou C
,
Huang Y
,
Cui M
,
de Vries RLA
,
Kim J
,
May J
,
Tocilescu MAleksandra
,
Liu W
,
Ko HSeok
et al.
. 2010.
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
.
Proc Natl Acad Sci U S A. 107(1):378-83.
Lewandowski NM
,
Ju S
,
Verbitsky M
,
Ross B
,
Geddie ML
,
Rockenstein E
,
Adame A
,
Muhammad A
,
Vonsattel JPaul
,
Ringe D
et al.
. 2010.
Polyamine pathway contributes to the pathogenesis of Parkinson disease.
.
Proc Natl Acad Sci U S A. 107(39):16970-5.
2009
Landon MR
,
Lieberman RL
,
Hoang QQ
,
Ju S
,
Caaveiro JMM
,
Orwig SD
,
Kozakov D
,
Brenke R
,
Chuang G-Y
,
Beglov D
et al.
. 2009.
Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase.
.
J Comput Aided Mol Des. 23(8):491-500.
Li Y
,
Liu W
,
Oo TF
,
Wang L
,
Tang Y
,
Jackson-Lewis V
,
Zhou C
,
Geghman K
,
Bogdanov M
,
Przedborski S
et al.
. 2009.
Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.
.
Nat Neurosci. 12(7):826-8.
2006
Zhou W
,
Zhu M
,
Wilson MA
,
Petsko GA
,
Fink AL
. 2006.
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.
.
J Mol Biol. 356(4):1036-48.
Das C
,
Hoang QQ
,
Kreinbring CA
,
Luchansky SJ
,
Meray RK
,
Ray SS
,
Lansbury PT
,
Ringe D
,
Petsko GA
. 2006.
Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.
.
Proc Natl Acad Sci U S A. 103(12):4675-80.