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Found 14 results
Author
Title
Type
[
Year
]
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Keyword
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Humans
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Author
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Petsko, Gregory A
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2013
Auclair JR
,
Johnson JL
,
Liu Q
,
Salisbury JP
,
Rotunno MS
,
Petsko GA
,
Ringe D
,
Brown RH
,
Bosco DA
,
Agar JN
. 2013.
Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.
.
Biochemistry. 52(36):6137-44.
Shim J-H
,
Greenblatt MB
,
Zou W
,
Huang Z
,
Wein MN
,
Brady N
,
Hu D
,
Charron J
,
Brodkin HR
,
Petsko GA
et al.
. 2013.
Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts.
.
J Clin Invest. 123(9):4010-22.
2012
Davies CW
,
Chaney J
,
Korbel G
,
Ringe D
,
Petsko GA
,
Ploegh H
,
Das C
. 2012.
The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK).
.
Bioorg Med Chem Lett. 22(12):3900-4.
2011
Bosco DA
,
LaVoie MJ
,
Petsko GA
,
Ringe D
. 2011.
Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.
.
Cold Spring Harb Perspect Biol. 3(10):a007500.
2010
Lewandowski NM
,
Ju S
,
Verbitsky M
,
Ross B
,
Geddie ML
,
Rockenstein E
,
Adame A
,
Muhammad A
,
Vonsattel JPaul
,
Ringe D
et al.
. 2010.
Polyamine pathway contributes to the pathogenesis of Parkinson disease.
.
Proc Natl Acad Sci U S A. 107(39):16970-5.
Auclair JR
,
Boggio KJ
,
Petsko GA
,
Ringe D
,
Agar JN
. 2010.
Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis.
.
Proc Natl Acad Sci U S A. 107(50):21394-9.
2009
Landon MR
,
Lieberman RL
,
Hoang QQ
,
Ju S
,
Caaveiro JMM
,
Orwig SD
,
Kozakov D
,
Brenke R
,
Chuang G-Y
,
Beglov D
et al.
. 2009.
Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase.
.
J Comput Aided Mol Des. 23(8):491-500.
Lieberman RL
,
J D'Aquino A
,
Ringe D
,
Petsko GA
. 2009.
Effects of pH and iminosugar pharmacological chaperones on lysosomal glycosidase structure and stability.
.
Biochemistry. 48(22):4816-27.
Ringe D
,
Petsko GA
. 2009.
What are pharmacological chaperones and why are they interesting?
J Biol. 8(9):80.
2007
Lieberman RL
,
Wustman BA
,
Huertas P
,
Powe AC
,
Pine CW
,
Khanna R
,
Schlossmacher MG
,
Ringe D
,
Petsko GA
. 2007.
Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.
.
Nat Chem Biol. 3(2):101-7.
2006
Zhou W
,
Zhu M
,
Wilson MA
,
Petsko GA
,
Fink AL
. 2006.
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.
.
J Mol Biol. 356(4):1036-48.
Das C
,
Hoang QQ
,
Kreinbring CA
,
Luchansky SJ
,
Meray RK
,
Ray SS
,
Lansbury PT
,
Ringe D
,
Petsko GA
. 2006.
Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.
.
Proc Natl Acad Sci U S A. 103(12):4675-80.
2005
Beilina A
,
Van Der Brug M
,
Ahmad R
,
Kesavapany S
,
Miller DW
,
Petsko GA
,
Cookson MR
. 2005.
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability.
.
Proc Natl Acad Sci U S A. 102(16):5703-8.
2004
Canet-Avilés RM
,
Wilson MA
,
Miller DW
,
Ahmad R
,
McLendon C
,
Bandyopadhyay S
,
Baptista MJ
,
Ringe D
,
Petsko GA
,
Cookson MR
. 2004.
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
.
Proc Natl Acad Sci U S A. 101(24):9103-8.