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2
Fargo KN
,
Aisen P
,
Albert M
,
Au R
,
Corrada MM
,
DeKosky S
,
Drachman D
,
Fillit H
,
Gitlin L
,
Haas M
et al.
. 2014.
2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.
.
Alzheimers Dement. 10(5 Suppl):S430-52.
Fargo KN
,
Aisen P
,
Albert M
,
Au R
,
Corrada MM
,
DeKosky S
,
Drachman D
,
Fillit H
,
Gitlin L
,
Haas M
et al.
. 2014.
2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.
.
Alzheimers Dement. 10(5 Suppl):S430-52.
Wong MYing
,
Lewis M
,
Doherty JJ
,
Shi Y
,
Cashikar AG
,
Amelianchik A
,
Tymchuk S
,
Sullivan PM
,
Qian M
,
Covey DF
et al.
. 2020.
25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.
.
J Neuroinflammation. 17(1):192.
A
Caballero B
,
Bourdenx M
,
Luengo E
,
Diaz A
,
Sohn PDongmin
,
Chen X
,
Wang C
,
Juste YR
,
Wegmann S
,
Patel B
et al.
. 2021.
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
.
Nat Commun. 12(1):2238.
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
Naseri NN
,
Ergel B
,
Kharel P
,
Na Y
,
Huang Q
,
Huang R
,
Dolzhanskaya N
,
Burré J
,
Velinov MT
,
Sharma M
. 2020.
Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.
.
Nat Struct Mol Biol. 27(2):192-201.
Das M
,
Mao W
,
Voskobiynyk Y
,
Necula D
,
Lew I
,
Petersen C
,
Zahn A
,
Yu G-Q
,
Yu X
,
Smith N
et al.
. 2023.
Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.
.
Neurobiol Dis. 186:106263.
DeMattos RB
,
Cirrito JR
,
Parsadanian M
,
May PC
,
O'dell MA
,
Taylor JW
,
Harmony JAK
,
Aronow BJ
,
Bales KR
,
Paul SM
et al.
. 2004.
ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.
.
Neuron. 41(2):193-202.
Shi Y
,
Yamada K
,
Liddelow SAntony
,
Smith ST
,
Zhao L
,
Luo W
,
Tsai RM
,
Spina S
,
Grinberg LT
,
Rojas JC
et al.
. 2017.
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
.
Nature. 549(7673):523-527.
Bales KR
,
Verina T
,
Cummins DJ
,
Du Y
,
Dodel RC
,
Saura J
,
Fishman CE
,
DeLong CA
,
Piccardo P
,
Petegnief V
et al.
. 1999.
Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 96(26):15233-8.
Bales KR
,
Verina T
,
Cummins DJ
,
Du Y
,
Dodel RC
,
Saura J
,
Fishman CE
,
DeLong CA
,
Piccardo P
,
Petegnief V
et al.
. 1999.
Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 96(26):15233-8.
Bales KR
,
Verina T
,
Cummins DJ
,
Du Y
,
Dodel RC
,
Saura J
,
Fishman CE
,
DeLong CA
,
Piccardo P
,
Petegnief V
et al.
. 1999.
Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 96(26):15233-8.
Doyle JP
,
Dougherty JD
,
Heiman M
,
Schmidt EF
,
Stevens TR
,
Ma G
,
Bupp S
,
Shrestha P
,
Shah RD
,
Doughty ML
et al.
. 2008.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
.
Cell. 135(4):749-62.
Doyle JP
,
Dougherty JD
,
Heiman M
,
Schmidt EF
,
Stevens TR
,
Ma G
,
Bupp S
,
Shrestha P
,
Shah RD
,
Doughty ML
et al.
. 2008.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
.
Cell. 135(4):749-62.
Doyle JP
,
Dougherty JD
,
Heiman M
,
Schmidt EF
,
Stevens TR
,
Ma G
,
Bupp S
,
Shrestha P
,
Shah RD
,
Doughty ML
et al.
. 2008.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
.
Cell. 135(4):749-62.
Auclair JR
,
Salisbury JP
,
Johnson JL
,
Petsko GA
,
Ringe D
,
Bosco DA
,
Agar NYR
,
Santagata S
,
Durham HD
,
Agar JN
. 2014.
Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.
.
Proteomics. 14(10):1152-7.
Limbad C
,
Oron TRonnen
,
Alimirah F
,
Davalos AR
,
Tracy TE
,
Gan L
,
Desprez P-Y
,
Campisi J
. 2020.
Astrocyte senescence promotes glutamate toxicity in cortical neurons.
.
PLoS One. 15(1):e0227887.
Limbad C
,
Oron TRonnen
,
Alimirah F
,
Davalos AR
,
Tracy TE
,
Gan L
,
Desprez P-Y
,
Campisi J
. 2020.
Astrocyte senescence promotes glutamate toxicity in cortical neurons.
.
PLoS One. 15(1):e0227887.
Barnett D
,
Bohmbach K
,
Grelot V
,
Charlet A
,
Dallérac G
,
Ju YHa
,
Nagai J
,
Orr AG
. 2023.
Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting.
.
J Neurosci. 43(45):7463-7471.
Orr AG
,
Hsiao EC
,
Wang MM
,
Ho K
,
Kim DH
,
Wang X
,
Guo W
,
Kang J
,
Yu G-Q
,
Adame A
et al.
. 2015.
Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
.
Nat Neurosci. 18(3):423-34.
Orr AG
,
Hsiao EC
,
Wang MM
,
Ho K
,
Kim DH
,
Wang X
,
Guo W
,
Kang J
,
Yu G-Q
,
Adame A
et al.
. 2015.
Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
.
Nat Neurosci. 18(3):423-34.
B
McKnight NC
,
Zhong Y
,
Wold MS
,
Gong S
,
Phillips GR
,
Dou Z
,
Zhao Y
,
Heintz N
,
Zong W-X
,
Yue Z
. 2014.
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
.
PLoS Genet. 10(10):e1004626.
Inoue K
,
Deng Z
,
Chen Y
,
Giannopoulou E
,
Xu R
,
Gong S
,
Greenblatt MB
,
Mangala LS
,
Lopez-Berestein G
,
Kirsch DG
et al.
. 2018.
Bone protection by inhibition of microRNA-182.
.
Nat Commun. 9(1):4108.
DeMattos RB
,
Bales KR
,
Cummins DJ
,
Paul SM
,
Holtzman DM
. 2002.
Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.
.
Science. 295(5563):2264-7.
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