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Found 15 results
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Tracy, Tara E
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A
Sohn PDongmin
,
Tracy TE
,
Son H-I
,
Zhou Y
,
Leite REP
,
Miller BL
,
Seeley WW
,
Grinberg LT
,
Gan L
. 2016.
Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.
.
Mol Neurodegener. 11(1):47.
Tracy TE
,
Gan L
. 2017.
Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy.
.
Bioessays. 39(4)
Tracy TE
,
Sohn PDongmin
,
S Minami S
,
Wang C
,
Min S-W
,
Li Y
,
Zhou Y
,
Le D
,
Lo I
,
Ponnusamy R
et al.
. 2016.
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
.
Neuron. 90(2):245-60.
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
Limbad C
,
Oron TRonnen
,
Alimirah F
,
Davalos AR
,
Tracy TE
,
Gan L
,
Desprez P-Y
,
Campisi J
. 2020.
Astrocyte senescence promotes glutamate toxicity in cortical neurons.
.
PLoS One. 15(1):e0227887.
C
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
K
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2023.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
bioRxiv.
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2024.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
J Clin Invest. 134(3)
N
Martinez-Losa M
,
Tracy TE
,
Ma K
,
Verret L
,
Clemente-Perez A
,
Khan AS
,
Cobos I
,
Ho K
,
Gan L
,
Mucke L
et al.
. 2018.
Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease.
.
Neuron. 98(1):75-89.e5.
P
Sohn PDongmin
,
Huang CTzu-Ling
,
Yan R
,
Fan L
,
Tracy TE
,
Camargo CM
,
Montgomery KM
,
Arhar T
,
Mok S-A
,
Freilich R
et al.
. 2019.
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
.
Neuron.
R
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
S
Wang C
,
Ward ME
,
Chen R
,
Liu K
,
Tracy TE
,
Chen X
,
Xie M
,
Sohn PDongmin
,
Ludwig C
,
Meyer-Franke A
et al.
. 2017.
Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.
.
Stem Cell Reports. 9(4):1221-1233.
T
Udeochu JC
,
Amin S
,
Huang Y
,
Fan L
,
Torres ERuth S
,
Carling GK
,
Liu B
,
McGurran H
,
Coronas-Samano G
,
Kauwe G
et al.
. 2023.
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
.
Nat Neurosci. 26(5):737-750.
Tracy TE
,
Madero-Pérez J
,
Swaney DL
,
Chang TS
,
Moritz M
,
Konrad C
,
Ward ME
,
Stevenson E
,
Huttenhain R
,
Kauwe G
et al.
. 2022.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
.
Cell. 185(4):712-728.e14.
Tracy TE
,
Gan L
. 2018.
Tau-mediated synaptic and neuronal dysfunction in neurodegenerative disease.
.
Curr Opin Neurobiol. 51:134-138.