Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 410 results

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Min S-W, Cho S-H, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C et al.. 2010. Acetylation of tau inhibits its degradation and contributes to tauopathy.. Neuron. 67(6):953-66.

Tracy TE, Sohn PDongmin, S Minami S, Wang C, Min S-W, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R et al.. 2016. Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.. Neuron. 90(2):245-60.

Caballero B, Bourdenx M, Luengo E, Diaz A, Sohn PDongmin, Chen X, Wang C, Juste YR, Wegmann S, Patel B et al.. 2021. Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.. Nat Commun. 12(1):2238.

Tracy TE, Gan L. 2017. Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy.. Bioessays. 39(4)

Sohn PDongmin, Tracy TE, Son H-I, Zhou Y, Leite REP, Miller BL, Seeley WW, Grinberg LT, Gan L. 2016. Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.. Mol Neurodegener. 11(1):47.

Wang C-E, Tydlacka S, Orr AL, Yang S-H, Graham RK, Hayden MR, Li S, Chan AWS, Li X-J. 2008. Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.. Hum Mol Genet. 17(17):2738-51.

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Sha SJ, Miller ZA, Min S-W, Zhou Y, Brown J, Mitic LL, Karydas A, Koestler M, Tsai R, Corbetta-Rastelli C et al.. 2017. An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from gene mutations.. Alzheimers Dement (N Y). 3(4):507-512.

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Lai CF, Gong SC, Esteban M. 1991. The 32-kilodalton envelope protein of vaccinia virus synthesized in Escherichia coli binds with specificity to cell surfaces.. J Virol. 65(1):499-504.

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Wong MYing, Lewis M, Doherty JJ, Shi Y, Cashikar AG, Amelianchik A, Tymchuk S, Sullivan PM, Qian M, Covey DF et al.. 2020. 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.. J Neuroinflammation. 17(1):192.

Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M et al.. 2014. 2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.. Alzheimers Dement. 10(5 Suppl):S430-52.