Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 139 results
Author Title Type [ Year(Desc)]
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2025
Belchikov N, Hu W, Fan L, Joglekar A, He Y, Foord C, Jarroux J, Hsu J, Pollard S, Amin S et al..  2025.  A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.. Cell Rep. 44(9):116198.
Chen H, Fan L, Wong MYing, Ambaw YA, Zhu J, Norman K, Ye P, Foxe N, Zhu D, Wan Y et al..  2025.  STING-IFN-CH25H lipid axis links innate immune activation to tau pathology.. bioRxiv.
Chen H, Fan L, Wong MYing, Ambaw YA, Zhu J, Norman K, Ye P, Foxe N, Zhu D, Wan Y et al..  2025.  STING-IFN-CH25H lipid axis links innate immune activation to tau pathology.. bioRxiv.
Chen H, Fan L, Wong MYing, Ambaw YA, Zhu J, Norman K, Ye P, Foxe N, Zhu D, Wan Y et al..  2025.  STING-IFN-CH25H lipid axis links innate immune activation to tau pathology.. bioRxiv.
2026
Liu Y, Feng W, Aikedan A, Lee S-I, Bhagwat M, Nagiri RKumar, Wong MYing, Amin S, Qu W, Zhu J et al..  2026.  cGAS inhibition delays TDP-43-driven ALS Pathogenesis.. bioRxiv.
Liu Y, Feng W, Aikedan A, Lee S-I, Bhagwat M, Nagiri RKumar, Wong MYing, Amin S, Qu W, Zhu J et al..  2026.  cGAS inhibition delays TDP-43-driven ALS Pathogenesis.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Feng W, Aikedan A, Sinha SC, Gan L.  2026.  Expanding roles of cGAS-STING signaling in neuroinflammation.. J Clin Invest. 136(11)
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Davtyan H, Naguib S, Voskobiynyk Y, Chadarevian JPaul, Capocchi JK, Giacchino JL, Eskandari-Sedighi G, DeNittis V, Ford JB, Agababian A et al..  2026.  Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice.. Res Sq.
Davtyan H, Naguib S, Voskobiynyk Y, Chadarevian JPaul, Capocchi JK, Giacchino JL, Eskandari-Sedighi G, DeNittis V, Ford JB, Agababian A et al..  2026.  Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice.. Res Sq.