Helen & Robert Appel Alzheimer’s Disease Research Institute

We enhance care, provide support and strive to eliminate Alzheimer's disease through the advancement of research in our state-of-the-art laboratories.

Our Mission

News

Mapping Dementia-Linked Protein Interactions Yields Potential New Treatment Targets

We’re excited to share our latest research out in CellPress NOW! Using APEX and AP-MS proteomics, we mapped Tau interactomes that were modified by neuronal activity and FTD mutations in hiPSC-derived...

Targeting the Brain’s Immune Cells May Help Prevent or Treat Alzheimer’s Disease

Our recent study in Science Translational Medicine identifies a TREM2 R47H-specific microglial subpopulation in human AD brain and tauopathy mice, reminiscent of DAM and AKT hyperactivation which can...

The Ninth Annual Appel Alzheimer's Disease Research Institute Symposium is scheduled virtually on Tuesday, November 9th, 2021

The Ninth Annual Appel Alzheimer's Disease Research Institute Symposium is scheduled virtually on Tuesday, November 9th, 2021 from 2:30PM - 4:00PM.This is an outstanding annual event hosted by Dean...