Helen & Robert Appel Alzheimer’s Disease Research Institute

https://appel.weill.cornell.edu/news/congratulations-ritika-rohatgi-and-dr-li-fan-successful-complet

We enhance care, provide support and strive to eliminate Alzheimer's disease through the advancement of research in our state-of-the-art laboratories.

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Congratulations to Ritika Rohatgi and Dr. Li Fan on the Successful Completion of the 2026 Appel Summer Scholar Program

The Helen & Robert Appel Institute for Alzheimer's Disease Research is proud to congratulate Ritika Rohatgi and Dr. Li Fan on the successful completion of the 2026 Appel Summer Scholar Program....

Inflammation May Drive Dravet Syndrome, Offering a Potential New Treatment Target

Brain activity traces recorded from different brain regions show frequent seizure-like activity in Dravet mouse models (left), while Dravet moouse models with genetically reduced cGAS (right) show...

Research Shifts Toward Shared Mechanisms in Neurodegenerative Diseases

Pictured left to right: Dean Robert A. Harrington, Dr. Edward Lee, Dr. Sreeganga Chandra, Helen Appel, Dr. Li Gan and Dr. Anna Orr. Credit: Reece Taylor WilliamsAlzheimer’s disease may not be a...

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Uptake of tau fibrils (pink) by human microglia (green)

Protein aggregation cause by Munc-18 mutations

Spinal Cord Pathology

Microglia Repopulation

Rainbow Mouse

Microglia in transgenic brain

RNAscope

Axon initial segment (red) in human stem cell-derived neurons (green)

News

Congratulations to Ritika Rohatgi and Dr. Li Fan on the Successful Completion of the 2026 Appel Summer Scholar Program

Inflammation May Drive Dravet Syndrome, Offering a Potential New Treatment Target

Research Shifts Toward Shared Mechanisms in Neurodegenerative Diseases

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Wu Laboratory

Sinha Laboratory

Sharma Laboratory

Orr Laboratory

Burré Laboratory

Gan Laboratory