Helen & Robert Appel Alzheimer’s Disease Research Institute

We enhance care, provide support and strive to eliminate Alzheimer's disease through the advancement of research in our state-of-the-art laboratories.

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News

Congratulations! Second R01 from the NIH Awarded to Dr. Anna Orr’s team

Mitochondria are organelles that produce energy and participate in normal intracellular signaling. However, they also release free radicals that can impair neural cells and promote disorders of the...

Congratulations! New R01 from NIH awarded to Dr. Wenjie Luo

DAP12 (also called TYROBP) acts as an adaptor protein in microglia involved in the cross-interaction of signaling networks of microglial surface immune receptors, including AD risk gene TREM2. DAP12...

Congratulations! New R01 from NIH Awarded to Dr. Anna Orr

TDP-43 is a nucleic acid-binding protein linked to neurodegenerative disorders, but its roles in non-neuronal cells like astrocytes are poorly understood. The proposed research will examine how...