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Found 325 results
Author
Title
Type
[
Year
]
2022
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Blackwell DJ
,
Faggioni M
,
Wleklinski MJ
,
Gomez-Hurtado N
,
Venkataraman R
,
Gibbs CE
,
Baudenbacher FJ
,
Gong S
,
Fishman GI
,
Boyle PM
et al.
. 2022.
The Purkinje-myocardial junction is the anatomical origin of ventricular arrhythmia in CPVT.
.
JCI Insight.
Hardwick SA
,
Hu W
,
Joglekar A
,
Fan L
,
Collier PG
,
Foord C
,
Balacco J
,
Lanjewar S
,
Sampson MMcGuirk
,
Koopmans F
et al.
. 2022.
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue.
.
Nat Biotechnol.
Tracy TE
,
Madero-Pérez J
,
Swaney DL
,
Chang TS
,
Moritz M
,
Konrad C
,
Ward ME
,
Stevenson E
,
Huttenhain R
,
Kauwe G
et al.
. 2022.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
.
Cell. 185(4):712-728.e14.
2021
Caballero B
,
Bourdenx M
,
Luengo E
,
Diaz A
,
Sohn PDongmin
,
Chen X
,
Wang C
,
Juste YR
,
Wegmann S
,
Patel B
et al.
. 2021.
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
.
Nat Commun. 12(1):2238.
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
Murava ALicht
,
Meadows S
,
Palaguachi F
,
Song SC
,
Bram Y
,
Zhou C
,
Schwartz RE
,
Froemke RC
,
Orr AL
,
Orr AG
. 2021.
Dementia-linked TDP-43 dysregulation in astrocytes impairs memory, antiviral signaling, and chemokine-mediated astrocytic-neuronal interactions.
.
Alzheimers Dement. 17 Suppl 2:e058562.
Xu P
,
Chang JC
,
Zhou X
,
Wang W
,
Bamkole M
,
Wong E
,
Bettayeb K
,
Jiang L-L
,
Huang T
,
Luo W
et al.
. 2021.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
.
J Exp Med. 218(8)
Singh SKumar
,
Kumar S
,
Viswakarma N
,
Principe DR
,
Das S
,
Sondarva G
,
Nair RSathish
,
Srivastava P
,
Sinha SC
,
Grippo PJ
et al.
. 2021.
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3.
.
Oncogene. 40(43):6153-6165.
Yang F
,
Li J
,
Song Y
,
Zhao M
,
Niemeyer JE
,
Luo P
,
Li D
,
Lin W
,
Ma H
,
Schwartz TH
. 2021.
Mesoscopic Mapping of Ictal Neurovascular Coupling in Awake Behaving Mice Using Optical Spectroscopy and Genetically Encoded Calcium Indicators.
.
Front Neurosci. 15:704834.
Viswakarma N
,
Sondarva G
,
Principe DR
,
Nair RSathish
,
Kumar S
,
Singh SKumar
,
Das S
,
Sinha SC
,
Grippo PJ
,
Grimaldo S
et al.
. 2021.
Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development.
.
Cancer Lett. 515:1-13.
Du H
,
Wong MYing
,
Zhang T
,
Santos MNunez
,
Hsu C
,
Zhang J
,
Yu H
,
Luo W
,
Hu F
. 2021.
A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.
.
Life Sci Alliance. 4(7)
Amin S
,
Carling G
,
Gan L
. 2021.
New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia.
.
Curr Opin Neurobiol. 72:131-139.
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
Lopez-Lee C
,
Kodama L
,
Gan L
. 2021.
Sex Differences in Neurodegeneration: The Role of the Immune System in Humans.
.
Biol Psychiatry.
2020
Wong MYing
,
Lewis M
,
Doherty JJ
,
Shi Y
,
Cashikar AG
,
Amelianchik A
,
Tymchuk S
,
Sullivan PM
,
Qian M
,
Covey DF
et al.
. 2020.
25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.
.
J Neuroinflammation. 17(1):192.
Naseri NN
,
Ergel B
,
Kharel P
,
Na Y
,
Huang Q
,
Huang R
,
Dolzhanskaya N
,
Burré J
,
Velinov MT
,
Sharma M
. 2020.
Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.
.
Nat Struct Mol Biol. 27(2):192-201.
Limbad C
,
Oron TRonnen
,
Alimirah F
,
Davalos AR
,
Tracy TE
,
Gan L
,
Desprez P-Y
,
Campisi J
. 2020.
Astrocyte senescence promotes glutamate toxicity in cortical neurons.
.
PLoS One. 15(1):e0227887.
Naseri N
,
Sharma M
,
Velinov M
. 2020.
Autosomal dominant neuronal ceroid lipofuscinosis: Clinical features and molecular basis.
.
Clin Genet.
Acosta-Ruiz A
,
Gutzeit VA
,
Skelly MJane
,
Meadows S
,
Lee J
,
Parekh P
,
Orr AG
,
Liston C
,
Pleil KE
,
Broichhagen J
et al.
. 2020.
Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo.
.
Neuron. 105(3):446-463.e13.
Telpoukhovskaia MA
,
Liu K
,
Sayed FA
,
Etchegaray JIker
,
Xie M
,
Zhan L
,
Li Y
,
Zhou Y
,
Le D
,
Bahr BA
et al.
. 2020.
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.
.
Sci Rep. 10(1):13688.
Inda MCarmen
,
Joshi S
,
Wang T
,
Bolaender A
,
Gandu S
,
Iii JKoren
,
Che AYue
,
Taldone T
,
Yan P
,
Sun W
et al.
. 2020.
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
.
Nat Commun. 11(1):319.
Heintz N
,
Gong S
. 2020.
Growth of and Preparation of DNA.
.
Cold Spring Harb Protoc. 2020(10)
Zhan L
,
Fan L
,
Kodama L
,
Sohn PDongmin
,
Wong MYing
,
Mousa GAlzaem
,
Zhou Y
,
Li Y
,
Gan L
. 2020.
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
.
Elife. 9
Kumar S
,
Singh SKumar
,
Viswakarma N
,
Sondarva G
,
Nair RSathish
,
Sethupathi P
,
Sinha SC
,
Emmadi R
,
Hoskins K
,
Danciu O
et al.
. 2020.
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
.
Proc Natl Acad Sci U S A. 117(14):7961-7970.
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