Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 376 results
Author Title Type [ Year(Desc)]
Filters: First Letter Of Last Name is G  [Clear All Filters]
2024
Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MBukar, Clelland CD, Cohen AD, Crary JF, Dage JL et al..  2024.  Novel avenues of tau research.. Alzheimers Dement.
Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MBukar, Clelland CD, Cohen AD, Crary JF, Dage JL et al..  2024.  Novel avenues of tau research.. Alzheimers Dement.
Netzer WJ, Sinha A, Ghias M, Chang E, Gindinova K, Mui E, Seo J-S, Sinha SC.  2024.  Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP.. Front Chem. 12:1381205.
Netzer WJ, Sinha A, Ghias M, Chang E, Gindinova K, Mui E, Seo J-S, Sinha SC.  2024.  Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP.. Front Chem. 12:1381205.
Lopez-Lee C, Kodama L, Fan L, Zhu D, Zhu J, Wong MYing, Ye P, Norman K, Foxe NR, Ijaz L et al..  2024.  Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.. Science. 386(6725):eadk7844.
Wang C, Zhang K, Cai B, Haller JE, Carnazza KE, Hu J, Zhao C, Tian Z, Hu X, Hall D et al..  2024.  VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates.. Nat Cell Biol. 26(8):1287-1295.
2025
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.. bioRxiv.
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.. bioRxiv.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Hu W, Foord C, Hsu J, Fan L, Corley MJ, Lanjewar SN, Xu S, Belchikov N, He Y, Pang APS et al..  2025.  Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state.. Nat Biotechnol.
Gao V, Crawford CV, Burré J.  2025.  Corrigendum: The Gut-Brain Axis in Parkinson's Disease.. Cold Spring Harb Perspect Med.
Sinha S, Gan L, Pieper AA.  2025.  Emerging approaches to bridging discovery science with clinical care in Alzheimer's disease.. Neurotherapeutics. 22(3):e00589.
Alarcón-Espósito J, Nagiri RKumar, Gan L, Sinha SC.  2025.  Identification and development of cGAS inhibitors and their uses to treat Alzheimer's disease.. Neurotherapeutics. 22(3):e00536.
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SHee, Hammock BD, Li H et al..  2025.  Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.. Mol Neurodegener. 20(1):44.
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SHee, Hammock BD, Li H et al..  2025.  Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.. Mol Neurodegener. 20(1):44.
Zhou C, Hardin EJ, Zimmer TS, Jackvony S, Barnett D, Khobrekar N, Giacomelli E, Studer L, Orr AL, Orr AG.  2025.  Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.. Neurobiol Dis. 211:106939.
Clelland CDudley, Fan L, Saloner R, Etchegaray JIker, Altobelli CRichard, Salomonsson S, Maltos AM, Sachdev A, Zhu J, Lee S-I et al..  2025.  Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.. Commun Biol. 8(1):971.
Clelland CDudley, Fan L, Saloner R, Etchegaray JIker, Altobelli CRichard, Salomonsson S, Maltos AM, Sachdev A, Zhu J, Lee S-I et al..  2025.  Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.. Commun Biol. 8(1):971.
Clelland CDudley, Fan L, Saloner R, Etchegaray JIker, Altobelli CRichard, Salomonsson S, Maltos AM, Sachdev A, Zhu J, Lee S-I et al..  2025.  Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.. Commun Biol. 8(1):971.
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.. Immunity. 58(8):1931-1947.e9.
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.. Immunity. 58(8):1931-1947.e9.
Mossa A, Dierdorff L, Lukin J, Garcia-Forn M, Wang W, Mamashli F, Park Y, Fiorenzani C, Akpinar Z, Kamps J et al..  2025.  Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X.. Nat Commun. 16(1):4512.
Gao V, Chlebowicz J, Gaskin K, Briano JA, Komer LE, Pineda A, Jhalani S, Ahmad S, Uwaifo E, Black LS et al..  2025.  Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy.. Nat Commun. 16(1):4079.