Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 212 results
Author Title Type [ Year(Desc)]
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2025
Clelland CDudley, Fan L, Saloner R, Etchegaray JIker, Altobelli CRichard, Salomonsson S, Maltos AM, Sachdev A, Zhu J, Lee S-I et al..  2025.  Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.. Commun Biol. 8(1):971.
Lee J, Kang R, Park S, Saliu IO, Son M, Voorhees JR, Dimitry JM, Quillin EI, Woodie LN, Lananna BV et al..  2025.  REV-ERBα regulates brain NAD+ levels and tauopathy via an NFIL3-CD38 axis.. Nat Aging. 5(10):2070-2085.
Mossa A, Dierdorff L, Lukin J, Garcia-Forn M, Wang W, Mamashli F, Park Y, Fiorenzani C, Akpinar Z, Kamps J et al..  2025.  Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X.. Nat Commun. 16(1):4512.
Naseri NN, Xu T, Chantarawong S, Patrie SM, Kelleher NL, Sharma M, Shalem O, Rhoades E.  2025.  Specific Combinations of Physiological Tau Phosphorylation Regulate Tau-Microtubule Interactions in Developing Neurons.. bioRxiv.
Gao V, Chlebowicz J, Gaskin K, Briano JA, Komer LE, Pineda A, Jhalani S, Ahmad S, Uwaifo E, Black LS et al..  2025.  Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy.. Nat Commun. 16(1):4079.
2026
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T et al..  2026.  CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. Cell. 189(5):1517-1534.e19.
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T et al..  2026.  CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. Cell. 189(5):1517-1534.e19.
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.