Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 325 results
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2014
Linsenbardt AJ, Taylor A, Emnett CM, Doherty JJ, Krishnan K, Covey DF, Paul SM, Zorumski CF, Mennerick S.  2014.  Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.. Neuropharmacology. 85:232-42.
Georgi B, Craig D, Kember RL, Liu W, Lindquist I, Nasser S, Brown C, Egeland JA, Paul SM, Bućan M.  2014.  Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.. PLoS Genet. 10(3):e1004229.
Georgi B, Craig D, Kember RL, Liu W, Lindquist I, Nasser S, Brown C, Egeland JA, Paul SM, Bućan M.  2014.  Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.. PLoS Genet. 10(3):e1004229.
Strauss KA, Markx S, Georgi B, Paul SM, Jinks RN, Hoshi T, McDonald A, First MB, Liu W, Benkert AR et al..  2014.  A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder.. Hum Mol Genet. 23(23):6395-406.
S Minami S, Min S-W, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME et al..  2014.  Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.. Nat Med. 20(10):1157-64.
Xiao L, Zhang C, Li X, Gong S, Hu R, Balasubramanian R, W WFCrowley, Hastings MH, Zhou Q-Y.  2014.  Signaling role of prokineticin 2 on the estrous cycle of female mice.. PLoS One. 9(3):e90860.
Kreinbring CA, Remillard SP, Hubbard P, Brodkin HR, Leeper FJ, Hawksley D, Lai EY, Fulton C, Petsko GA, Ringe D.  2014.  Structure of a eukaryotic thiaminase I.. Proc Natl Acad Sci U S A. 111(1):137-42.
Kreinbring CA, Remillard SP, Hubbard P, Brodkin HR, Leeper FJ, Hawksley D, Lai EY, Fulton C, Petsko GA, Ringe D.  2014.  Structure of a eukaryotic thiaminase I.. Proc Natl Acad Sci U S A. 111(1):137-42.
Lee SHun, Sharma M, Südhof TC, Shen J.  2014.  Synaptic function of nicastrin in hippocampal neurons.. Proc Natl Acad Sci U S A. 111(24):8973-8.
Hu X, Li X, Zhao M, Gottesdiener A, Luo W, Paul S.  2014.  Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.. Mol Neurodegener. 9:52.
Hu X, Li X, Zhao M, Gottesdiener A, Luo W, Paul S.  2014.  Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.. Mol Neurodegener. 9:52.
2013
Edayathumangalam R, Wu R, Garcia R, Wang Y, Wang W, Kreinbring CA, Bach A, Liao J, Stone TA, Terwilliger TC et al..  2013.  Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.. Proc Natl Acad Sci U S A. 110(44):17820-5.
Edayathumangalam R, Wu R, Garcia R, Wang Y, Wang W, Kreinbring CA, Bach A, Liao J, Stone TA, Terwilliger TC et al..  2013.  Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.. Proc Natl Acad Sci U S A. 110(44):17820-5.
Wu X, Gong S, Roy-Burman P, Lee P, Culig Z.  2013.  Current mouse and cell models in prostate cancer research.. Endocr Relat Cancer. 20(4):R155-70.
Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G et al..  2013.  Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.. Mol Psychiatry. 18(8):889-97.
Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G et al..  2013.  Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.. Mol Psychiatry. 18(8):889-97.
Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G et al..  2013.  Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.. Mol Psychiatry. 18(8):882-8.
Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G et al..  2013.  Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.. Mol Psychiatry. 18(8):882-8.
Paul SM, Doherty JJ, Robichaud AJ, Belfort GM, Chow BY, Hammond RS, Crawford DC, Linsenbardt AJ, Shu H-J, Izumi Y et al..  2013.  The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors.. J Neurosci. 33(44):17290-300.
Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R.  2013.  NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.. Neurosci Lett. 547:16-20.
Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R.  2013.  NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.. Neurosci Lett. 547:16-20.
Liu CFeng, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D.  2013.  A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.. Biochemistry. 52(9):1603-10.
Liu CFeng, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D.  2013.  A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.. Biochemistry. 52(9):1603-10.
Liu CFeng, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D.  2013.  A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.. Biochemistry. 52(9):1603-10.
Auclair JR, Johnson JL, Liu Q, Salisbury JP, Rotunno MS, Petsko GA, Ringe D, Brown RH, Bosco DA, Agar JN.  2013.  Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.. Biochemistry. 52(36):6137-44.