Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 87 results

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2024

Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al.. 2024. Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.

Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al.. 2024. Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.

Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al.. 2024. Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.

Rodriguez-Rodriguez P, Arroyo-Garcia LEnrique, Tsagkogianni C, Li L, Wang W, Végvári Á, Salas-Allende I, Plautz Z, Cedazo-Minguez A, Sinha SC et al.. 2024. A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.. Brain. 147(7):2384-2399.

Bravo CParra, Giani AMaria, Madero-Pérez J, Zhao Z, Wan Y, Samelson AJ, Wong MYing, Evangelisti A, Cordes E, Fan L et al.. 2024. Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. Cell. 187(10):2446-2464.e22.

Bravo CParra, Giani AMaria, Madero-Pérez J, Zhao Z, Wan Y, Samelson AJ, Wong MYing, Evangelisti A, Cordes E, Fan L et al.. 2024. Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. Cell. 187(10):2446-2464.e22.

Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y et al.. 2024. KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.. J Clin Invest. 134(3)

Liu Y, Jiang S, Li Y, Zhao S, Yun Z, Zhao Z-H, Zhang L, Wang G, Chen X, Manubens-Gil L et al.. 2024. Neuronal diversity and stereotypy at multiple scales through whole brain morphometry.. Nat Commun. 15(1):10269.

Lopez-Lee C, Kodama L, Fan L, Zhu D, Zhu J, Wong MYing, Ye P, Norman K, Foxe NR, Ijaz L et al.. 2024. Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.. Science. 386(6725):eadk7844.

Lopez-Lee C, Kodama L, Fan L, Zhu D, Zhu J, Wong MYing, Ye P, Norman K, Foxe NR, Ijaz L et al.. 2024. Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.. Science. 386(6725):eadk7844.

2025

Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al.. 2025. APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.. bioRxiv.

Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al.. 2025. Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.