Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 191 results
Author Title Type [ Year(Desc)]
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2025
Chen H, Fan L, Wong MYing, Ambaw YA, Zhu J, Norman K, Ye P, Foxe N, Zhu D, Wan Y et al..  2025.  STING-IFN-CH25H lipid axis links innate immune activation to tau pathology.. bioRxiv.
Gao V, Chlebowicz J, Gaskin K, Briano JA, Komer LE, Pineda A, Jhalani S, Ahmad S, Uwaifo E, Black LS et al..  2025.  Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy.. Nat Commun. 16(1):4079.
2026
Liu Y, Feng W, Aikedan A, Lee S-I, Bhagwat M, Nagiri RKumar, Wong MYing, Amin S, Qu W, Zhu J et al..  2026.  cGAS inhibition delays TDP-43-driven ALS Pathogenesis.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Li X, Chen Y, Wang H, Zhang X, Guiberson NGuy Lewis, Li X, Burré J, Peng J, Zhang H, Yue Z.  2026.  Disruption of the LRRK2 substrate RAB12 facilitates neurotransmission and causes hyperactivity in mice.. NPJ Parkinsons Dis. 12(1)
Li X, Chen Y, Wang H, Zhang X, Guiberson NGuy Lewis, Li X, Burré J, Peng J, Zhang H, Yue Z.  2026.  Disruption of the LRRK2 substrate RAB12 facilitates neurotransmission and causes hyperactivity in mice.. NPJ Parkinsons Dis. 12(1)
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Zolin A, Weber SA, Xie YXin, Burré J.  2026.  Propagation of α-synuclein pathology: models, mechanisms and future goals.. Mol Neurodegener Adv. 2(1):26.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Davtyan H, Naguib S, Voskobiynyk Y, Chadarevian JPaul, Capocchi JK, Giacchino JL, Eskandari-Sedighi G, DeNittis V, Ford JB, Agababian A et al..  2026.  Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice.. Res Sq.