Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 39 results
Author Title Type [ Year(Asc)]
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2010
Min S-W, Cho S-H, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C et al..  2010.  Acetylation of tau inhibits its degradation and contributes to tauopathy.. Neuron. 67(6):953-66.
Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC.  2010.  Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.. Science. 329(5999):1663-7.
2009
Orr AG, Orr AL, Li X-J, Gross RE, Traynelis SF.  2009.  Adenosine A(2A) receptor mediates microglial process retraction.. Nat Neurosci. 12(7):872-8.
2008
Wang C-E, Tydlacka S, Orr AL, Yang S-H, Graham RK, Hayden MR, Li S, Chan AWS, Li X-J.  2008.  Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.. Hum Mol Genet. 17(17):2738-51.
Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML et al..  2008.  Application of a translational profiling approach for the comparative analysis of CNS cell types.. Cell. 135(4):749-62.
2006
Burré J, Beckhaus T, Schägger H, Corvey C, Hofmann S, Karas M, Zimmermann H, Volknandt W.  2006.  Analysis of the synaptic vesicle proteome using three gel-based protein separation techniques.. Proteomics. 6(23):6250-62.
Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L et al..  2006.  Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease.. Neuron. 51(6):703-14.
2005
Nicole O, Goldshmidt A, Hamill CE, Sorensen SD, Sastre A, Lyuboslavsky P, Hepler JR, McKeon RJ, Traynelis SF.  2005.  Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.. J Neurosci. 25(17):4319-29.
Brendza RP, Bacskai BJ, Cirrito JR, Simmons KA, Skoch JM, Klunk WE, Mathis CA, Bales KR, Paul SM, Hyman BT et al..  2005.  Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.. J Clin Invest. 115(2):428-33.
2004
DeMattos RB, Cirrito JR, Parsadanian M, May PC, O'dell MA, Taylor JW, Harmony JAK, Aronow BJ, Bales KR, Paul SM et al..  2004.  ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.. Neuron. 41(2):193-202.
Koistinaho M, Lin S, Wu X, Esterman M, Koger D, Hanson J, Higgs R, Liu F, Malkani S, Bales KR et al..  2004.  Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.. Nat Med. 10(7):719-26.
2000
Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D et al..  2000.  Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.. Proc Natl Acad Sci U S A. 97(6):2892-7.
1999
Bales KR, Verina T, Cummins DJ, Du Y, Dodel RC, Saura J, Fishman CE, DeLong CA, Piccardo P, Petegnief V et al..  1999.  Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.. Proc Natl Acad Sci U S A. 96(26):15233-8.
1998
Wang LY, Gan L, Perney TM, Schwartz I, Kaczmarek LK.  1998.  Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion.. Proc Natl Acad Sci U S A. 95(4):1882-7.