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Found 36 results
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2024
Wallace CH
,
Oliveros G
,
Xie L
,
Serrano P
,
Rockwell P
,
Figueiredo-Pereira M
. 2024.
Potential Alzheimer's early biomarkers in a transgenic rat model and benefits of diazoxide/dibenzoylmethane co-treatment on spatial memory and AD-pathology.
.
Sci Rep. 14(1):3730.
2022
Blackwell DJ
,
Faggioni M
,
Wleklinski MJ
,
Gomez-Hurtado N
,
Venkataraman R
,
Gibbs CE
,
Baudenbacher FJ
,
Gong S
,
Fishman GI
,
Boyle PM
et al.
. 2022.
The Purkinje-myocardial junction is the anatomical origin of ventricular arrhythmia in CPVT.
.
JCI Insight.
2020
Luo W
,
Ip FCF
,
Fu G
,
Cheung K
,
Tian Y
,
Hu Y
,
Sinha A
,
Cheng EYL
,
Wu X
,
Bustos V
et al.
. 2020.
A Pentacyclic Triterpene from Targets γ-Secretase.
.
ACS Chem Neurosci. 11(18):2827-2835.
Chen X
,
Li Y
,
Wang C
,
Tang Y
,
Mok S-A
,
Tsai RM
,
Rojas JC
,
Karydas A
,
Miller BL
,
Boxer AL
et al.
. 2020.
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.
.
Mol Neurodegener. 15(1):2.
2019
Sohn PDongmin
,
Huang CTzu-Ling
,
Yan R
,
Fan L
,
Tracy TE
,
Camargo CM
,
Montgomery KM
,
Arhar T
,
Mok S-A
,
Freilich R
et al.
. 2019.
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
.
Neuron.
Xie L
,
Xie L
. 2019.
Pathway-Centric Structure-Based Multi-Target Compound Screening for Anti-Virulence Drug Repurposing.
.
Int J Mol Sci. 20(14)
Liu Q
,
He D
,
Xie L
. 2019.
Prediction of off-target specificity and cell-specific fitness of CRISPR-Cas System using attention boosted deep learning and network-based gene feature.
.
PLoS Comput Biol. 15(10):e1007480.
Lin L-C
,
Nana AL
,
Hepker M
,
Hwang J-HLee
,
Gaus SE
,
Spina S
,
Cosme CG
,
Gan L
,
Grinberg LT
,
Geschwind DH
et al.
. 2019.
Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants.
.
Acta Neuropathol Commun. 7(1):159.
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
2018
Wong H-S
,
Monternier P-A
,
Orr AL
,
Brand MD
. 2018.
Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria.
.
Methods Mol Biol. 1782:287-299.
A Willsey J
,
Morris MT
,
Wang S
,
Willsey HR
,
Sun N
,
Teerikorpi N
,
Baum TB
,
Cagney G
,
Bender KJ
,
Desai TA
et al.
. 2018.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
.
Cell. 174(3):505-520.
2014
Mecozzi VJ
,
Berman DE
,
Simoes S
,
Vetanovetz C
,
Awal MR
,
Patel VM
,
Schneider RT
,
Petsko GA
,
Ringe D
,
Small SA
. 2014.
Pharmacological chaperones stabilize retromer to limit APP processing.
.
Nat Chem Biol. 10(6):443-9.
Strauss KA
,
Markx S
,
Georgi B
,
Paul SM
,
Jinks RN
,
Hoshi T
,
McDonald A
,
First MB
,
Liu W
,
Benkert AR
et al.
. 2014.
A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder.
.
Hum Mol Genet. 23(23):6395-406.
Hey-Mogensen M
,
Goncalves RLS
,
Orr AL
,
Brand MD
. 2014.
Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria.
.
Free Radic Biol Med. 72:149-55.
S Minami S
,
Min S-W
,
Krabbe G
,
Wang C
,
Zhou Y
,
Asgarov R
,
Li Y
,
Martens LH
,
Elia LP
,
Ward ME
et al.
. 2014.
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
.
Nat Med. 20(10):1157-64.
2013
Liu CFeng
,
Liu D
,
Momb J
,
Thomas PW
,
Lajoie A
,
Petsko GA
,
Fast W
,
Ringe D
. 2013.
A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.
.
Biochemistry. 52(9):1603-10.
Kauppinen TM
,
Gan L
,
Swanson RA
. 2013.
Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.
.
Biochim Biophys Acta. 1833(8):1985-91.
Auclair JR
,
Johnson JL
,
Liu Q
,
Salisbury JP
,
Rotunno MS
,
Petsko GA
,
Ringe D
,
Brown RH
,
Bosco DA
,
Agar JN
. 2013.
Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.
.
Biochemistry. 52(36):6137-44.
Burré J
,
Vivona S
,
Diao J
,
Sharma M
,
Brunger AT
,
Südhof TC
. 2013.
Properties of native brain α-synuclein.
.
Nature. 498(7453):E4-6;discussionE6-7.
2012
Martens LHerl
,
Zhang J
,
Barmada SJ
,
Zhou P
,
Kamiya S
,
Sun B
,
Min S-W
,
Gan L
,
Finkbeiner S
,
Huang EJ
et al.
. 2012.
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
.
J Clin Invest. 122(11):3955-9.
Sharma M
,
Burré J
,
Südhof TC
. 2012.
Proteasome inhibition alleviates SNARE-dependent neurodegeneration.
.
Sci Transl Med. 4(147):147ra113.
2011
Liu W
,
Acín-Peréz R
,
Geghman KD
,
Manfredi G
,
Lu B
,
Li C
. 2011.
Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.
.
Proc Natl Acad Sci U S A. 108(31):12920-4.
Kauppinen TM
,
Suh SWon
,
Higashi Y
,
Berman AE
,
Escartin C
,
Won SJoon
,
Wang C
,
Cho S-H
,
Gan L
,
Swanson RA
. 2011.
Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.
.
J Neuroinflammation. 8:152.
Zhang F
,
Wang S
,
Gan L
,
Vosler PS
,
Gao Y
,
Zigmond MJ
,
Chen J
. 2011.
Protective effects and mechanisms of sirtuins in the nervous system.
.
Prog Neurobiol. 95(3):373-95.
Bosco DA
,
LaVoie MJ
,
Petsko GA
,
Ringe D
. 2011.
Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.
.
Cold Spring Harb Perspect Biol. 3(10):a007500.
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