Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 12 results
Author Title Type [ Year(Desc)]
Filters: Author is Mok, Sue-Ann  [Clear All Filters]
2018
Min S-W, Sohn PDongmin, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok S-A, Gestwicki JE, Gan L.  2018.  SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.. J Neurosci. 38(15):3680-3688.
2019
Sohn PDongmin, Huang CTzu-Ling, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok S-A, Freilich R et al..  2019.  Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.. Neuron.
2020
Chen X, Li Y, Wang C, Tang Y, Mok S-A, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL et al..  2020.  Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.. Mol Neurodegener. 15(1):2.
2022
Wang C, Fan L, Khawaja RR, Liu B, Zhan L, Kodama L, Chin M, Li Y, Le D, Zhou Y et al..  2022.  Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.. Nat Commun. 13(1):1969.
Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Huttenhain R, Kauwe G et al..  2022.  Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.. Cell. 185(4):712-728.e14.
2023
Chen H, Fan L, Guo Q, Wong MYing, Yu F, Foxe N, Wang W, Nessim A, Carling G, Liu B et al..  2023.  DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.. Res Sq.
Bravo CParra, Giani AMaria, Perez JMadero, Zhao Z, Samelson A, Wong MYing, Evangelisti A, Fan L, Pozner T, Mercedes M et al..  2023.  Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. bioRxiv.
Udeochu JC, Amin S, Huang Y, Fan L, Torres ERuth S, Carling GK, Liu B, McGurran H, Coronas-Samano G, Kauwe G et al..  2023.  Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.. Nat Neurosci. 26(5):737-750.
2024
Carling GK, Fan L, Foxe NR, Norman K, Wong MYing, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. Neuron.
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.
Bravo CParra, Giani AMaria, Madero-Pérez J, Zhao Z, Wan Y, Samelson AJ, Wong MYing, Evangelisti A, Cordes E, Fan L et al..  2024.  Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. Cell. 187(10):2446-2464.e22.
2025
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.. bioRxiv.