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Found 137 results
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2008
Doyle JP
,
Dougherty JD
,
Heiman M
,
Schmidt EF
,
Stevens TR
,
Ma G
,
Bupp S
,
Shrestha P
,
Shah RD
,
Doughty ML
et al.
. 2008.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
.
Cell. 135(4):749-62.
Doyle JP
,
Dougherty JD
,
Heiman M
,
Schmidt EF
,
Stevens TR
,
Ma G
,
Bupp S
,
Shrestha P
,
Shah RD
,
Doughty ML
et al.
. 2008.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
.
Cell. 135(4):749-62.
Sun B
,
Zhou Y
,
Halabisky B
,
Lo I
,
Cho S-H
,
Mueller-Steiner S
,
Devidze N
,
Wang X
,
Grubb A
,
Gan L
. 2008.
Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease.
.
Neuron. 60(2):247-57.
Heiman M
,
Schaefer A
,
Gong S
,
Peterson JD
,
Day M
,
Ramsey KE
,
Suárez-Fariñas M
,
Schwarz C
,
Stephan DA
,
D Surmeier J
et al.
. 2008.
A translational profiling approach for the molecular characterization of CNS cell types.
.
Cell. 135(4):738-48.
2007
Luo W
,
Dou F
,
Rodina A
,
Chip S
,
Kim J
,
Zhao Q
,
Moulick K
,
Aguirre J
,
Wu N
,
Greengard P
et al.
. 2007.
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
.
Proc Natl Acad Sci U S A. 104(22):9511-6.
Gong S
,
Doughty M
,
Harbaugh CR
,
Cummins A
,
Hatten ME
,
Heintz N
,
Gerfen CR
. 2007.
Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.
.
J Neurosci. 27(37):9817-23.
2006
Das C
,
Hoang QQ
,
Kreinbring CA
,
Luchansky SJ
,
Meray RK
,
Ray SS
,
Lansbury PT
,
Ringe D
,
Petsko GA
. 2006.
Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.
.
Proc Natl Acad Sci U S A. 103(12):4675-80.
2005
Du K
,
Sharma M
,
Lukacs GL
. 2005.
The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR.
.
Nat Struct Mol Biol. 12(1):17-25.
Dodart J-C
,
Marr RA
,
Koistinaho M
,
Gregersen BM
,
Malkani S
,
Verma IM
,
Paul SM
. 2005.
Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 102(4):1211-6.
Kaczmarek LK
,
Bhattacharjee A
,
Desai R
,
Gan L
,
Song P
,
von Hehn CAA
,
Whim MD
,
Yang B
. 2005.
Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels.
.
Hear Res. 206(1-2):133-45.
2004
DeMattos RB
,
Cirrito JR
,
Parsadanian M
,
May PC
,
O'dell MA
,
Taylor JW
,
Harmony JAK
,
Aronow BJ
,
Bales KR
,
Paul SM
et al.
. 2004.
ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.
.
Neuron. 41(2):193-202.
Liang Y
,
Lin S
,
Beyer TP
,
Zhang Y
,
Wu X
,
Bales KR
,
DeMattos RB
,
May PC
,
Li SDan
,
Jiang X-C
et al.
. 2004.
A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes.
.
J Neurochem. 88(3):623-34.
Sharma M
,
Pampinella F
,
Nemes C
,
Benharouga M
,
So J
,
Du K
,
Bache KG
,
Papsin B
,
Zerangue N
,
Stenmark H
et al.
. 2004.
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes.
.
J Cell Biol. 164(6):923-33.
2003
Benharouga M
,
Sharma M
,
So J
,
Haardt M
,
Drzymala L
,
Popov M
,
Schwapach B
,
Grinstein S
,
Du K
,
Lukacs GL
. 2003.
The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia.
.
J Biol Chem. 278(24):22079-89.
Benharouga M
,
Sharma M
,
So J
,
Haardt M
,
Drzymala L
,
Popov M
,
Schwapach B
,
Grinstein S
,
Du K
,
Lukacs GL
. 2003.
The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia.
.
J Biol Chem. 278(24):22079-89.
2002
DeMattos RB
,
Bales KR
,
Cummins DJ
,
Paul SM
,
Holtzman DM
. 2002.
Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.
.
Science. 295(5563):2264-7.
DeMattos RB
,
O'dell MA
,
Parsadanian M
,
Taylor JW
,
Harmony JAK
,
Bales KR
,
Paul SM
,
Aronow BJ
,
Holtzman DM
. 2002.
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 99(16):10843-8.
Dodart J-C
,
Bales KR
,
Gannon KS
,
Greene SJ
,
DeMattos RB
,
Mathis C
,
DeLong CA
,
Wu S
,
Wu X
,
Holtzman DM
et al.
. 2002.
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.
.
Nat Neurosci. 5(5):452-7.
Dodart J-C
,
Bales KR
,
Gannon KS
,
Greene SJ
,
DeMattos RB
,
Mathis C
,
DeLong CA
,
Wu S
,
Wu X
,
Holtzman DM
et al.
. 2002.
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.
.
Nat Neurosci. 5(5):452-7.
Dodart J-C
,
Bales KR
,
Gannon KS
,
Greene SJ
,
DeMattos RB
,
Mathis C
,
DeLong CA
,
Wu S
,
Wu X
,
Holtzman DM
et al.
. 2002.
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.
.
Nat Neurosci. 5(5):452-7.
2001
DeMattos RB
,
Bales KR
,
Cummins DJ
,
Dodart JC
,
Paul SM
,
Holtzman DM
. 2001.
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 98(15):8850-5.
DeMattos RB
,
Bales KR
,
Cummins DJ
,
Dodart JC
,
Paul SM
,
Holtzman DM
. 2001.
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 98(15):8850-5.
2000
Lechardeur D
,
Drzymala L
,
Sharma M
,
Zylka D
,
Kinach R
,
Pacia J
,
Hicks C
,
Usmani N
,
Rommens JM
,
Lukacs GL
. 2000.
Determinants of the nuclear localization of the heterodimeric DNA fragmentation factor (ICAD/CAD).
.
J Cell Biol. 150(2):321-34.
Bales KR
,
Du Y
,
Holtzman D
,
Cordell B
,
Paul SM
. 2000.
Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.
.
Neurobiol Aging. 21(3):427-32;discussion451-3.
Heymont J
,
Berenfeld L
,
Collins J
,
Kaganovich A
,
Maynes B
,
Moulin A
,
Ratskovskaya I
,
Poon PP
,
Johnston GC
,
Kamenetsky M
et al.
. 2000.
TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation.
.
Proc Natl Acad Sci U S A. 97(23):12672-7.
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