Title | AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation. |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Sayed FA, Kodama L, Fan L, Carling GK, Udeochu JC, Le D, Li Q, Zhou L, Wong MYing, Horowitz R, Ye P, Mathys H, Wang M, Niu X, Mazutis L, Jiang X, Wang X, Gao F, Brendel M, Telpoukhovskaia M, Tracy TE, Frost G, Zhou Y, Li Y, Qiu Y, Cheng Z, Yu G, Hardy J, Coppola G, Wang F, DeTure MA, Zhang B, Xie L, Trajnowski JQ, M Y Lee V, Gong S, Sinha SC, Dickson DW, Luo W, Gan L |
Journal | Sci Transl Med |
Volume | 13 |
Issue | 622 |
Pagination | eabe3947 |
Date Published | 2021 Dec |
ISSN | 1946-6242 |
Abstract | [Figure: see text]. |
DOI | 10.1126/scitranslmed.abe3947 |
Alternate Journal | Sci Transl Med |
PubMed ID | 34851693 |