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Found 173 results
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2018
Guiberson NGuy Lewis
,
Pineda A
,
Abramov D
,
Kharel P
,
Carnazza KE
,
Wragg RT
,
Dittman JS
,
Burré J
. 2018.
Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
.
Nat Commun. 9(1):3986.
Martinez-Losa M
,
Tracy TE
,
Ma K
,
Verret L
,
Clemente-Perez A
,
Khan AS
,
Cobos I
,
Ho K
,
Gan L
,
Mucke L
et al.
. 2018.
Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease.
.
Neuron. 98(1):75-89.e5.
A Willsey J
,
Morris MT
,
Wang S
,
Willsey HR
,
Sun N
,
Teerikorpi N
,
Baum TB
,
Cagney G
,
Bender KJ
,
Desai TA
et al.
. 2018.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
.
Cell. 174(3):505-520.
A Willsey J
,
Morris MT
,
Wang S
,
Willsey HR
,
Sun N
,
Teerikorpi N
,
Baum TB
,
Cagney G
,
Bender KJ
,
Desai TA
et al.
. 2018.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
.
Cell. 174(3):505-520.
A Willsey J
,
Morris MT
,
Wang S
,
Willsey HR
,
Sun N
,
Teerikorpi N
,
Baum TB
,
Cagney G
,
Bender KJ
,
Desai TA
et al.
. 2018.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
.
Cell. 174(3):505-520.
A Willsey J
,
Morris MT
,
Wang S
,
Willsey HR
,
Sun N
,
Teerikorpi N
,
Baum TB
,
Cagney G
,
Bender KJ
,
Desai TA
et al.
. 2018.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
.
Cell. 174(3):505-520.
Gupta I
,
Collier PG
,
Haase B
,
Mahfouz A
,
Joglekar A
,
Floyd T
,
Koopmans F
,
Barres B
,
Smit AB
,
Sloan SA
et al.
. 2018.
Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells.
.
Nat Biotechnol.
Min S-W
,
Sohn PDongmin
,
Li Y
,
Devidze N
,
Johnson JR
,
Krogan NJ
,
Masliah E
,
Mok S-A
,
Gestwicki JE
,
Gan L
. 2018.
SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.
.
J Neurosci. 38(15):3680-3688.
2019
Karch CM
,
Kao AW
,
Karydas A
,
Onanuga K
,
Martinez R
,
Argouarch A
,
Wang C
,
Huang C
,
Sohn PDongmin
,
Bowles KR
et al.
. 2019.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
.
Stem Cell Reports.
Karch CM
,
Kao AW
,
Karydas A
,
Onanuga K
,
Martinez R
,
Argouarch A
,
Wang C
,
Huang C
,
Sohn PDongmin
,
Bowles KR
et al.
. 2019.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
.
Stem Cell Reports.
Karch CM
,
Kao AW
,
Karydas A
,
Onanuga K
,
Martinez R
,
Argouarch A
,
Wang C
,
Huang C
,
Sohn PDongmin
,
Bowles KR
et al.
. 2019.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
.
Stem Cell Reports.
Karch CM
,
Kao AW
,
Karydas A
,
Onanuga K
,
Martinez R
,
Argouarch A
,
Wang C
,
Huang C
,
Sohn PDongmin
,
Bowles KR
et al.
. 2019.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
.
Stem Cell Reports.
Kodama L
,
Gan L
. 2019.
Do Microglial Sex Differences Contribute to Sex Differences in Neurodegenerative Diseases?
Trends Mol Med.
Kodama L
,
Guzman E
,
Etchegaray JI
,
Li Y
,
Sayed FA
,
Zhou L
,
Zhou Y
,
Zhan L
,
Le D
,
Udeochu JC
et al.
. 2019.
Microglial microRNAs mediate sex-specific responses to tau pathology.
.
Nat Neurosci.
Kodama L
,
Guzman E
,
Etchegaray JI
,
Li Y
,
Sayed FA
,
Zhou L
,
Zhou Y
,
Zhan L
,
Le D
,
Udeochu JC
et al.
. 2019.
Microglial microRNAs mediate sex-specific responses to tau pathology.
.
Nat Neurosci.
Orr AL
,
Kim C
,
Jimenez-Morales D
,
Newton BW
,
Johnson JR
,
Krogan NJ
,
Swaney DL
,
Mahley RW
. 2019.
Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function.
.
J Alzheimers Dis. 68(3):991-1011.
Orr AL
,
Kim C
,
Jimenez-Morales D
,
Newton BW
,
Johnson JR
,
Krogan NJ
,
Swaney DL
,
Mahley RW
. 2019.
Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function.
.
J Alzheimers Dis. 68(3):991-1011.
Sohn PDongmin
,
Huang CTzu-Ling
,
Yan R
,
Fan L
,
Tracy TE
,
Camargo CM
,
Montgomery KM
,
Arhar T
,
Mok S-A
,
Freilich R
et al.
. 2019.
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
.
Neuron.
Sohn PDongmin
,
Huang CTzu-Ling
,
Yan R
,
Fan L
,
Tracy TE
,
Camargo CM
,
Montgomery KM
,
Arhar T
,
Mok S-A
,
Freilich R
et al.
. 2019.
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.
.
Neuron.
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
Lim H
,
He D
,
Qiu Y
,
Krawczuk P
,
Sun X
,
Xie L
. 2019.
Rational discovery of dual-indication multi-target PDE/Kinase inhibitor for precision anti-cancer therapy using structural systems pharmacology.
.
PLoS Comput Biol. 15(6):e1006619.
2020
Naseri NN
,
Ergel B
,
Kharel P
,
Na Y
,
Huang Q
,
Huang R
,
Dolzhanskaya N
,
Burré J
,
Velinov MT
,
Sharma M
. 2020.
Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.
.
Nat Struct Mol Biol. 27(2):192-201.
Inda MCarmen
,
Joshi S
,
Wang T
,
Bolaender A
,
Gandu S
,
Iii JKoren
,
Che AYue
,
Taldone T
,
Yan P
,
Sun W
et al.
. 2020.
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
.
Nat Commun. 11(1):319.
Zhan L
,
Fan L
,
Kodama L
,
Sohn PDongmin
,
Wong MYing
,
Mousa GAlzaem
,
Zhou Y
,
Li Y
,
Gan L
. 2020.
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
.
Elife. 9
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