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Found 173 results
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Journal Article
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Viswakarma N
,
Sondarva G
,
Principe DR
,
Nair RSathish
,
Kumar S
,
Singh SKumar
,
Das S
,
Sinha SC
,
Grippo PJ
,
Grimaldo S
et al.
. 2021.
Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development.
.
Cancer Lett. 515:1-13.
Kumar S
,
Singh SKumar
,
Viswakarma N
,
Sondarva G
,
Nair RSathish
,
Sethupathi P
,
Sinha SC
,
Emmadi R
,
Hoskins K
,
Danciu O
et al.
. 2020.
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
.
Proc Natl Acad Sci U S A. 117(14):7961-7970.
Krabbe G
,
S Minami S
,
Etchegaray JI
,
Taneja P
,
Djukic B
,
Davalos D
,
Le D
,
Lo I
,
Zhan L
,
Reichert MC
et al.
. 2017.
Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.
.
Proc Natl Acad Sci U S A. 114(19):5029-5034.
Wang C
,
Fan L
,
Khawaja RR
,
Liu B
,
Zhan L
,
Kodama L
,
Chin M
,
Li Y
,
Le D
,
Zhou Y
et al.
. 2022.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
.
Nat Commun. 13(1):1969.
Wang C
,
Fan L
,
Khawaja RR
,
Liu B
,
Zhan L
,
Kodama L
,
Chin M
,
Li Y
,
Le D
,
Zhou Y
et al.
. 2022.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
.
Nat Commun. 13(1):1969.
Kodama L
,
Guzman E
,
Etchegaray JI
,
Li Y
,
Sayed FA
,
Zhou L
,
Zhou Y
,
Zhan L
,
Le D
,
Udeochu JC
et al.
. 2019.
Microglial microRNAs mediate sex-specific responses to tau pathology.
.
Nat Neurosci.
Kodama L
,
Guzman E
,
Etchegaray JI
,
Li Y
,
Sayed FA
,
Zhou L
,
Zhou Y
,
Zhan L
,
Le D
,
Udeochu JC
et al.
. 2019.
Microglial microRNAs mediate sex-specific responses to tau pathology.
.
Nat Neurosci.
Guiberson NGuy Lewis
,
Pineda A
,
Abramov D
,
Kharel P
,
Carnazza KE
,
Wragg RT
,
Dittman JS
,
Burré J
. 2018.
Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
.
Nat Commun. 9(1):3986.
Singh SKumar
,
Kumar S
,
Viswakarma N
,
Principe DR
,
Das S
,
Sondarva G
,
Nair RSathish
,
Srivastava P
,
Sinha SC
,
Grippo PJ
et al.
. 2021.
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3.
.
Oncogene. 40(43):6153-6165.
Zhao L
,
Lin S
,
Bales KR
,
Gelfanova V
,
Koger D
,
DeLong C
,
Hale J
,
Liu F
,
Hunter JM
,
Paul SM
. 2009.
Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism.
.
J Neurosci. 29(11):3603-12.
Zhan L
,
Fan L
,
Kodama L
,
Sohn PDongmin
,
Wong MYing
,
Mousa GAlzaem
,
Zhou Y
,
Li Y
,
Gan L
. 2020.
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
.
Elife. 9
Xie YXue
,
Naseri NN
,
Fels J
,
Kharel P
,
Na Y
,
Lane D
,
Burré J
,
Sharma M
. 2022.
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
.
Nat Commun. 13(1):4918.
Bhattacharjee A
,
Gan L
,
Kaczmarek LK
. 2002.
Localization of the Slack potassium channel in the rat central nervous system.
.
J Comp Neurol. 454(3):241-54.
Steele JW
,
Ju S
,
Lachenmayer ML
,
Liken J
,
Stock A
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.
.
Mol Psychiatry. 18(8):882-8.
Steele JW
,
Lachenmayer ML
,
Ju S
,
Stock A
,
Liken J
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.
.
Mol Psychiatry. 18(8):889-97.
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2023.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
bioRxiv.
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2024.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
J Clin Invest. 134(3)
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2023.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
bioRxiv.
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2024.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
J Clin Invest. 134(3)
Orr AG
,
Lo I
,
Schumacher H
,
Ho K
,
Gill M
,
Guo W
,
Kim DH
,
Knox A
,
Saito T
,
Saido TC
et al.
. 2018.
Istradefylline reduces memory deficits in aging mice with amyloid pathology.
.
Neurobiol Dis. 110:29-36.
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