Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 398 results

]

Filters: Essential-evidence-based-introductory-bioterrorism-content-practicing-nurses is [Clear All Filters]

2024

Pfau SJ, Langen UH, Fisher TM, Prakash I, Nagpurwala F, Lozoya RA, Lee W-CAllen, Wu Z, Gu C. 2024. Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells.. Nat Neurosci. 27(10):1892-1903.

Iannone AF, Akgül G, Zhang R, Wacks S, Hussein N, Macias CGinelly, Donatelle A, Bauriedel JMJ, Wright C, Abramov D et al.. 2024. The chemokine Cxcl14 regulates interneuron differentiation in layer I of the somatosensory cortex.. Cell Rep. 43(8):114531.

Buchholz S, Bell-Simons M, Cakmak C, Klimek J, Gan L, Zempel H. 2024. Cultivation, Differentiation, and Lentiviral Transduction of Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Glutamatergic Neurons for Studying Human Tau.. Methods Mol Biol. 2754:533-549.

Guiberson NGuy Lewis, Black LS, Haller JE, Brukner A, Abramov D, Ahmad S, Xie YXin, Sharma M, Burré J. 2024. Disease-linked mutations in Munc18-1 deplete synaptic Doc2.. Brain.

Oostrom M, Muniak MA, West RMEichler, Akers S, Pande P, Obiri M, Wang W, Bowyer K, Wu Z, Bramer LM et al.. 2024. Fine-tuning TrailMap: The utility of transfer learning to improve the performance of deep learning in axon segmentation of light-sheet microscopy images.. PLoS One. 19(3):e0293856.

Gao V, Crawford CV, Burré J. 2024. The Gut-Brain Axis in Parkinson's Disease.. Cold Spring Harb Perspect Med.

Meadows SM, Palaguachi F, Jang MWendy, Licht-Murava A, Barnett D, Zimmer TS, Zhou C, McDonough SR, Orr AL, Orr AG. 2024. Hippocampal astrocytes induce sex-dimorphic effects on memory.. Cell Rep. 43(6):114278.

Bravo CParra, Giani AMaria, Madero-Pérez J, Zhao Z, Wan Y, Samelson AJ, Wong MYing, Evangelisti A, Cordes E, Fan L et al.. 2024. Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. Cell. 187(10):2446-2464.e22.

Kauwe G, Pareja-Navarro KA, Yao L, Chen JH, Wong I, Saloner R, Cifuentes H, Nana AL, Shah S, Li Y et al.. 2024. KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.. J Clin Invest. 134(3)

Zheng X, Wu B, Liu Y, Simmons SK, Kim K, Clarke GS, Ashiq A, Park J, Li J, Wang Z et al.. 2024. Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development.. Cell. 187(13):3236-3248.e21.

Lopez-Lee C, Torres ERuth S, Carling G, Gan L. 2024. Mechanisms of sex differences in Alzheimer's disease.. Neuron.

Hanzel M, Fernando K, Maloney SE, Horn Z, Gong S, Mätlik K, Zhao J, H Pasolli A, Heissel S, Dougherty JD et al.. 2024. Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties.. Proc Natl Acad Sci U S A. 121(34):e2405901121.

Wang C, Zhao C, Hu X, Qiang J, Liu Z, Gu J, Zhang S, Li D, Zhang Y, Burré J et al.. 2024. N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine.. bioRxiv.

Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR et al.. 2024. Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids.. PNAS Nexus. 3(5):pgae179.

Fridy PC, Farrell RJ, Molloy KR, Keegan S, Wang J, Jacobs EY, Li Y, Trivedi J, Sehgal V, Fenyö D et al.. 2024. A new generation of nanobody research tools using improved mass spectrometry-based discovery methods.. J Biol Chem. 300(9):107623.

Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MBukar, Clelland CD, Cohen AD, Crary JF, Dage JL et al.. 2024. Novel avenues of tau research.. Alzheimers Dement.

Wallace CH, Oliveros G, Xie L, Serrano P, Rockwell P, Figueiredo-Pereira M. 2024. Potential Alzheimer's early biomarkers in a transgenic rat model and benefits of diazoxide/dibenzoylmethane co-treatment on spatial memory and AD-pathology.. Sci Rep. 14(1):3730.

Bustos VHugo, Sunkari YKrishna, Sinha A, Pulina M, Bispo A, Hopkins M, Lam A, Kriegsman SF, Mui E, Chang E et al.. 2024. Rational Development of a Small-Molecule Activator of CK1γ2 That Decreases C99 and Beta-Amyloid Levels.. ACS Chem Biol. 19(1):37-47.

Burré J, Edwards RH, Halliday G, Lang AE, Lashuel HA, Melki R, Murayama S, Outeiro TF, Papa SM, Stefanis L et al.. 2024. Research Priorities on the Role of α-Synuclein in Parkinson's Disease Pathogenesis.. Mov Disord. 39(10):1663-1678.

Netzer WJ, Sinha A, Ghias M, Chang E, Gindinova K, Mui E, Seo J-S, Sinha SC. 2024. Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP.. Front Chem. 12:1381205.

Bennett NK, Lee M, Orr AL, Nakamura K. 2024. Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production.. Proc Natl Acad Sci U S A. 121(3):e2307904121.

Lopez-Lee C, Kodama L, Fan L, Zhu D, Zhu J, Wong MYing, Ye P, Norman K, Foxe NR, Ijaz L et al.. 2024. Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.. Science. 386(6725):eadk7844.

Wang C, Zhang K, Cai B, Haller JE, Carnazza KE, Hu J, Zhao C, Tian Z, Hu X, Hall D et al.. 2024. VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates.. Nat Cell Biol. 26(8):1287-1295.