Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 256 results
Author Title Type [ Year(Asc)]
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2026
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Davtyan H, Naguib S, Voskobiynyk Y, Chadarevian JPaul, Capocchi JK, Giacchino JL, Eskandari-Sedighi G, DeNittis V, Ford JB, Agababian A et al..  2026.  Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice.. Res Sq.
2025
Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S et al..  2025.  Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.. Alzheimers Dement. 21(1):e14291.
Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S et al..  2025.  Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.. Alzheimers Dement. 21(1):e14291.
Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S et al..  2025.  Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.. Alzheimers Dement. 21(1):e14291.
Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S et al..  2025.  Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.. Alzheimers Dement. 21(1):e14291.
Jati S, Taheri S, Kal S, Sinha SC, Head BP, Mahata SK, Sahoo D.  2025.  Boolean Network Modeling Identifies Cognitive Resilience in the First Murine Model of Asymptomatic Alzheimer's Disease.. bioRxiv.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Hu W, Foord C, Hsu J, Fan L, Corley MJ, Lanjewar SN, Xu S, Belchikov N, He Y, Pang APS et al..  2025.  Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state.. Nat Biotechnol.
Hu W, Foord C, Hsu J, Fan L, Corley MJ, Lanjewar SN, Xu S, Belchikov N, He Y, Pang APS et al..  2025.  Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state.. Nat Biotechnol.
Hu W, Foord C, Hsu J, Fan L, Corley MJ, Lanjewar SN, Xu S, Belchikov N, He Y, Pang APS et al..  2025.  Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state.. Nat Biotechnol.
Chen H, Fan L, Guo Q, Wong MYing, Zhu J, Foxe N, Wang W, Nessim A, Carling G, Liu B et al..  2025.  DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice.. Mol Neurodegener. 20(1):124.
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SHee, Hammock BD, Li H et al..  2025.  Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.. Mol Neurodegener. 20(1):44.
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SHee, Hammock BD, Li H et al..  2025.  Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.. Mol Neurodegener. 20(1):44.
Zhou C, Hardin EJ, Zimmer TS, Jackvony S, Barnett D, Khobrekar N, Giacomelli E, Studer L, Orr AL, Orr AG.  2025.  Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.. Neurobiol Dis. 211:106939.
Belchikov N, Hu W, Fan L, Joglekar A, He Y, Foord C, Jarroux J, Hsu J, Pollard S, Amin S et al..  2025.  A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.. Cell Rep. 44(9):116198.
Belchikov N, Hu W, Fan L, Joglekar A, He Y, Foord C, Jarroux J, Hsu J, Pollard S, Amin S et al..  2025.  A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.. Cell Rep. 44(9):116198.
Belchikov N, Hu W, Fan L, Joglekar A, He Y, Foord C, Jarroux J, Hsu J, Pollard S, Amin S et al..  2025.  A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.. Cell Rep. 44(9):116198.
Gao V, Chlebowicz J, Gaskin K, Briano JA, Komer LE, Pineda A, Jhalani S, Ahmad S, Uwaifo E, Black LS et al..  2025.  Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathy.. Nat Commun. 16(1):4079.
2024
Carling GK, Fan L, Foxe NR, Norman K, Wong MYing, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. Neuron.