Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 242 results
Author Title Type [ Year(Desc)]
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2004
Koistinaho M, Lin S, Wu X, Esterman M, Koger D, Hanson J, Higgs R, Liu F, Malkani S, Bales KR et al..  2004.  Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.. Nat Med. 10(7):719-26.
Gresch O, Engel FB, Nesic D, Tran TThai, England HM, Hickman ES, Körner I, Gan L, Chen S, Castro-Obregon S et al..  2004.  New non-viral method for gene transfer into primary cells.. Methods. 33(2):151-63.
Gresch O, Engel FB, Nesic D, Tran TThai, England HM, Hickman ES, Körner I, Gan L, Chen S, Castro-Obregon S et al..  2004.  New non-viral method for gene transfer into primary cells.. Methods. 33(2):151-63.
2005
Nicole O, Goldshmidt A, Hamill CE, Sorensen SD, Sastre A, Lyuboslavsky P, Hepler JR, McKeon RJ, Traynelis SF.  2005.  Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.. J Neurosci. 25(17):4319-29.
Nicole O, Goldshmidt A, Hamill CE, Sorensen SD, Sastre A, Lyuboslavsky P, Hepler JR, McKeon RJ, Traynelis SF.  2005.  Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.. J Neurosci. 25(17):4319-29.
Brendza RP, Bacskai BJ, Cirrito JR, Simmons KA, Skoch JM, Klunk WE, Mathis CA, Bales KR, Paul SM, Hyman BT et al..  2005.  Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.. J Clin Invest. 115(2):428-33.
Brendza RP, Bacskai BJ, Cirrito JR, Simmons KA, Skoch JM, Klunk WE, Mathis CA, Bales KR, Paul SM, Hyman BT et al..  2005.  Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice.. J Clin Invest. 115(2):428-33.
Wahrle SE, Jiang H, Parsadanian M, Hartman RE, Bales KR, Paul SM, Holtzman DM.  2005.  Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.. J Biol Chem. 280(52):43236-42.
Wahrle SE, Jiang H, Parsadanian M, Hartman RE, Bales KR, Paul SM, Holtzman DM.  2005.  Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.. J Biol Chem. 280(52):43236-42.
Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CAF, Breiderhoff T, Jansen P, Wu X et al..  2005.  Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.. Proc Natl Acad Sci U S A. 102(38):13461-6.
Gu X, Li C, Wei W, Lo V, Gong S, Li S-H, Iwasato T, Itohara S, Li X-J, Mody I et al..  2005.  Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.. Neuron. 46(3):433-44.
Hamill CE, Goldshmidt A, Nicole O, McKeon RJ, Brat DJ, Traynelis SF.  2005.  Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery.. Clin Neurosurg. 52:29-44.
Cirrito JR, Yamada KA, Finn MBeth, Sloviter RS, Bales KR, May PC, Schoepp DD, Paul SM, Mennerick S, Holtzman DM.  2005.  Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.. Neuron. 48(6):913-22.
2006
Burré J, Beckhaus T, Schägger H, Corvey C, Hofmann S, Karas M, Zimmermann H, Volknandt W.  2006.  Analysis of the synaptic vesicle proteome using three gel-based protein separation techniques.. Proteomics. 6(23):6250-62.
Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XWilliam, Heintz N, Lin S.  2006.  Modified bacterial artificial chromosomes for zebrafish transgenesis.. Methods. 39(3):183-8.
Das C, Hoang QQ, Kreinbring CA, Luchansky SJ, Meray RK, Ray SS, Lansbury PT, Ringe D, Petsko GA.  2006.  Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.. Proc Natl Acad Sci U S A. 103(12):4675-80.
2007
Head K, Gong S, Joseph S, Wang C, Burkhardt T, Rossi MR, LaDuca J, Matsui S-I, Vaughan M, Hicks DG et al..  2007.  Defining the expression pattern of the LGI1 gene in BAC transgenic mice.. Mamm Genome. 18(5):328-37.
Head K, Gong S, Joseph S, Wang C, Burkhardt T, Rossi MR, LaDuca J, Matsui S-I, Vaughan M, Hicks DG et al..  2007.  Defining the expression pattern of the LGI1 gene in BAC transgenic mice.. Mamm Genome. 18(5):328-37.
Head K, Gong S, Joseph S, Wang C, Burkhardt T, Rossi MR, LaDuca J, Matsui S-I, Vaughan M, Hicks DG et al..  2007.  Defining the expression pattern of the LGI1 gene in BAC transgenic mice.. Mamm Genome. 18(5):328-37.
Tomishima MJ, Hadjantonakis A-K, Gong S, Studer L.  2007.  Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library.. Stem Cells. 25(1):39-45.
Lieberman RL, Wustman BA, Huertas P, Powe AC, Pine CW, Khanna R, Schlossmacher MG, Ringe D, Petsko GA.  2007.  Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.. Nat Chem Biol. 3(2):101-7.
Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR.  2007.  Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.. J Neurosci. 27(37):9817-23.
Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR.  2007.  Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.. J Neurosci. 27(37):9817-23.
Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR.  2007.  Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.. J Neurosci. 27(37):9817-23.
2008
Wang C-E, Tydlacka S, Orr AL, Yang S-H, Graham RK, Hayden MR, Li S, Chan AWS, Li X-J.  2008.  Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.. Hum Mol Genet. 17(17):2738-51.