Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 257 results
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2016
Tracy TE, Sohn PDongmin, S Minami S, Wang C, Min S-W, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R et al..  2016.  Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.. Neuron. 90(2):245-60.
Möller T, Bard F, Bhattacharya A, Biber K, Campbell B, Dale E, Eder C, Gan L, Garden GA, Hughes ZA et al..  2016.  Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.. Glia. 64(10):1788-94.
Brand MD, Goncalves RLS, Orr AL, Vargas L, Gerencser AA, Jensen MBorch, Wang YT, Melov S, Turk CN, Matzen JT et al..  2016.  Suppressors of Superoxide-HO Production at Site I of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.. Cell Metab. 24(4):582-592.
Brand MD, Goncalves RLS, Orr AL, Vargas L, Gerencser AA, Jensen MBorch, Wang YT, Melov S, Turk CN, Matzen JT et al..  2016.  Suppressors of Superoxide-HO Production at Site I of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.. Cell Metab. 24(4):582-592.
Brand MD, Goncalves RLS, Orr AL, Vargas L, Gerencser AA, Jensen MBorch, Wang YT, Melov S, Turk CN, Matzen JT et al..  2016.  Suppressors of Superoxide-HO Production at Site I of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.. Cell Metab. 24(4):582-592.
2015
Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu G-Q, Adame A et al..  2015.  Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.. Nat Neurosci. 18(3):423-34.
Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu G-Q, Adame A et al..  2015.  Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.. Nat Neurosci. 18(3):423-34.
Min S-W, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, S Minami S, Defensor E, Mok SAnn et al..  2015.  Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.. Nat Med. 21(10):1154-62.
Min S-W, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, S Minami S, Defensor E, Mok SAnn et al..  2015.  Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.. Nat Med. 21(10):1154-62.
Min S-W, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, S Minami S, Defensor E, Mok SAnn et al..  2015.  Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.. Nat Med. 21(10):1154-62.
Min S-W, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, S Minami S, Defensor E, Mok SAnn et al..  2015.  Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.. Nat Med. 21(10):1154-62.
S Minami S, Shen V, Le D, Krabbe G, Asgarov R, Perez-Celajes L, Lee C-H, Li J, Donnelly-Roberts D, Gan L.  2015.  Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.. Biochem Pharmacol. 97(4):454-462.
Cho S-H, Chen JA, Sayed F, Ward ME, Gao F, Nguyen TA, Krabbe G, Sohn PDongmin, Lo I, Minami S et al..  2015.  SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.. J Neurosci. 35(2):807-18.
Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RLS et al..  2015.  Suppressors of superoxide production from mitochondrial complex III.. Nat Chem Biol. 11(11):834-6.
Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RLS et al..  2015.  Suppressors of superoxide production from mitochondrial complex III.. Nat Chem Biol. 11(11):834-6.
Bacaj T, Wu D, Burré J, Malenka RC, Liu X, Südhof TC.  2015.  Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles.. PLoS Biol. 13(10):e1002267.
Kim KHye, Liu J, Galvin RJSells, Dage JL, Egeland JA, Smith RC, Merchant KM, Paul SM.  2015.  Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.. PLoS One. 10(11):e0142693.
2014
Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M et al..  2014.  2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.. Alzheimers Dement. 10(5 Suppl):S430-52.
Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M et al..  2014.  2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.. Alzheimers Dement. 10(5 Suppl):S430-52.
Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M et al..  2014.  2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.. Alzheimers Dement. 10(5 Suppl):S430-52.
Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M et al..  2014.  2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.. Alzheimers Dement. 10(5 Suppl):S430-52.
Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M et al..  2014.  2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.. Alzheimers Dement. 10(5 Suppl):S430-52.
McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong W-X, Yue Z.  2014.  Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.. PLoS Genet. 10(10):e1004626.
Linsenbardt AJ, Taylor A, Emnett CM, Doherty JJ, Krishnan K, Covey DF, Paul SM, Zorumski CF, Mennerick S.  2014.  Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.. Neuropharmacology. 85:232-42.
Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LHerl, Seeley WW et al..  2014.  Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.. J Exp Med. 211(10):1937-45.