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Military-related risk factors for dementia.

TitleMilitary-related risk factors for dementia.
Publication TypeJournal Article
Year of Publication2018
AuthorsSnyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR, Jaffee M, Lamb BT, Landau S, Manley G, McKee A, Perl D, Schneider JA, Weiner M, Wellington C, Yaffe K, Bain L, Pacifico AM, Carrillo MC
JournalAlzheimers Dement
Volume14
Issue12
Pagination1651-1662
Date Published2018 Dec
ISSN1552-5279
Abstract

INTRODUCTION: In recent years, there has been growing discussion to better understand the pathophysiological mechanisms of traumatic brain injury and post-traumatic stress disorder and how they may be linked to an increased risk of neurodegenerative diseases including Alzheimer's disease in veterans.

METHODS: Building on that discussion, and subsequent to a special issue of Alzheimer's & Dementia published in June 2014, which focused on military risk factors, the Alzheimer's Association convened a continued discussion of the scientific community on December 1, 2016.

RESULTS: During this meeting, participants presented and evaluated progress made since 2012 and identified outstanding knowledge gaps regarding factors that may impact veterans' risk for later life dementia.

DISCUSSION: The following is a summary of the invited presentations and moderated discussions of both the review of scientific understanding and identification of gaps to inform further investigations.

DOI10.1016/j.jalz.2018.08.011
Alternate JournalAlzheimers Dement
PubMed ID30415806
PubMed Central IDPMC6281800
Grant ListR01 AG022374 / AG / NIA NIH HHS / United States
R56 AG058913 / AG / NIA NIH HHS / United States
R01 AG013616 / AG / NIA NIH HHS / United States
R01 AG062348 / AG / NIA NIH HHS / United States
P30 AG013846 / AG / NIA NIH HHS / United States
R01 AG012101 / AG / NIA NIH HHS / United States
P50 AG047266 / AG / NIA NIH HHS / United States
K23 NS095755 / NS / NINDS NIH HHS / United States
RF1 AG057570 / AG / NIA NIH HHS / United States
R01 AG054214 / AG / NIA NIH HHS / United States
RF1 AG057902 / AG / NIA NIH HHS / United States