Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 136 results
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2025
Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S et al..  2025.  Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.. Alzheimers Dement. 21(1):e14291.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al..  2025.  Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.
Wang Z, Lipshutz A, de la Torre CMartínez, Trzeciak AJ, Liu Z-L, Miranda IC, Lazarov T, Codo AC, Romero-Pichardo JE, Nair A et al..  2025.  Early life high fructose impairs microglial phagocytosis and neurodevelopment.. Nature. 644(8077):759-768.
Wang Z, Lipshutz A, de la Torre CMartínez, Trzeciak AJ, Liu Z-L, Miranda IC, Lazarov T, Codo AC, Romero-Pichardo JE, Nair A et al..  2025.  Early life high fructose impairs microglial phagocytosis and neurodevelopment.. Nature. 644(8077):759-768.
Wang S, Qi C, Rajpurohit C, Ghosh B, Xiong W, Wang B, Qi Y, Hwang SHee, Hammock BD, Li H et al..  2025.  Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.. Mol Neurodegener. 20(1):44.
Clelland CDudley, Fan L, Saloner R, Etchegaray JIker, Altobelli CRichard, Salomonsson S, Maltos AM, Sachdev A, Zhu J, Lee S-I et al..  2025.  Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.. Commun Biol. 8(1):971.
Belchikov N, Hu W, Fan L, Joglekar A, He Y, Foord C, Jarroux J, Hsu J, Pollard S, Amin S et al..  2025.  A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.. Cell Rep. 44(9):116198.
Belchikov N, Hu W, Fan L, Joglekar A, He Y, Foord C, Jarroux J, Hsu J, Pollard S, Amin S et al..  2025.  A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.. Cell Rep. 44(9):116198.
Naseri NN, Xu T, Chantarawong S, Patrie SM, Kelleher NL, Sharma M, Shalem O, Rhoades E.  2025.  Specific Combinations of Physiological Tau Phosphorylation Regulate Tau-Microtubule Interactions in Developing Neurons.. bioRxiv.
2026
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T et al..  2026.  CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. Cell. 189(5):1517-1534.e19.
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T et al..  2026.  CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. Cell. 189(5):1517-1534.e19.