Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 398 results
Author Title Type [ Year(Asc)]
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2026
Liu Y, Feng W, Aikedan A, Lee S-I, Bhagwat M, Nagiri RKumar, Wong MYing, Amin S, Qu W, Zhu J et al..  2026.  cGAS inhibition delays TDP-43-driven ALS Pathogenesis.. bioRxiv.
Liu Y, Feng W, Aikedan A, Lee S-I, Bhagwat M, Nagiri RKumar, Wong MYing, Amin S, Qu W, Zhu J et al..  2026.  cGAS inhibition delays TDP-43-driven ALS Pathogenesis.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz M, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.. bioRxiv.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz MP, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.. Nat Neurosci.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz MP, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.. Nat Neurosci.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz MP, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.. Nat Neurosci.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz MP, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.. Nat Neurosci.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz MP, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.. Nat Neurosci.
Huang Y, Fan L, Wong MYing, Lei Z, Krishnamachary B, Zhu D, Cadiz MP, Nagiri RKumar, Ye P, Norman K et al..  2026.  cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.. Nat Neurosci.
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T et al..  2026.  CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. Cell. 189(5):1517-1534.e19.
Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T et al..  2026.  CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. Cell. 189(5):1517-1534.e19.
Li X, Chen Y, Wang H, Zhang X, Guiberson NGuy Lewis, Li X, Burré J, Peng J, Zhang H, Yue Z.  2026.  Disruption of the LRRK2 substrate RAB12 facilitates neurotransmission and causes hyperactivity in mice.. NPJ Parkinsons Dis. 12(1)
Li X, Chen Y, Wang H, Zhang X, Guiberson NGuy Lewis, Li X, Burré J, Peng J, Zhang H, Yue Z.  2026.  Disruption of the LRRK2 substrate RAB12 facilitates neurotransmission and causes hyperactivity in mice.. NPJ Parkinsons Dis. 12(1)
Qu W, Fan L, Jang MWendy, Ye P, Cordes E, Aikedan A, Hu W, Nagiri RKumar, Wong MYing, Luo W et al..  2026.  Humanized tauopathy chimeras uncover microglial and lncRNA strategies for neuroprotection.. bioRxiv.
Castagnola C, Marongiu R, Wan Y, Torres ERuth S, Fan L, Jang MWendy, Cui Q, Kim J, Ye P, Zhu J et al..  2026.  Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.. bioRxiv.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
Pan J-P, Wang P-J, Zhang J, Knapskog A-B, Watne LOtto, Wang H-L, Lagartos-Donate MJose, Lautrup S, Mao L-P, Wang Q et al..  2026.  Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.. Nat Aging. 6(5):1079-1102.
2025
Kloske CM, Mahinrad S, Barnum CJ, Batista AF, Bradshaw EM, Butts B, Carrillo MC, Chakrabarty P, Chen X, Craft S et al..  2025.  Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.. Alzheimers Dement. 21(1):e14291.