TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

TitleTREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
Publication TypeJournal Article
Year of Publication2016
AuthorsYuan P, Condello C, C Keene D, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J
JournalNeuron
Volume92
Issue1
Pagination252-264
Date Published2016 10 05
ISSN1097-4199
DOI10.1016/j.neuron.2016.09.016
Alternate JournalNeuron
PubMed ID27710785
Grant ListP30 AG019610 / AG / NIA NIH HHS / United States
U24 NS072026 / NS / NINDS NIH HHS / United States