Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 8 results
Author Title Type [ Year(Asc)]
Filters: Keyword is Inflammation  [Clear All Filters]
2023
Oliveros G, Wallace CH, Chaudry O, Liu Q, Qiu Y, Xie L, Rockwell P, Figueiredo-Pereira ME, Serrano PA.  2023.  Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation.. Brain. 146(3):898-911.
2017
Shi Y, Yamada K, Liddelow SAntony, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC et al..  2017.  ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.. Nature. 549(7673):523-527.
2015
S Minami S, Shen V, Le D, Krabbe G, Asgarov R, Perez-Celajes L, Lee C-H, Li J, Donnelly-Roberts D, Gan L.  2015.  Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.. Biochem Pharmacol. 97(4):454-462.
2012
Martens LHerl, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min S-W, Gan L, Finkbeiner S, Huang EJ et al..  2012.  Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.. J Clin Invest. 122(11):3955-9.
2007
Gan L.  2007.  Therapeutic potential of sirtuin-activating compounds in Alzheimer's disease.. Drug News Perspect. 20(4):233-9.
2005
Hamill CE, Goldshmidt A, Nicole O, McKeon RJ, Brat DJ, Traynelis SF.  2005.  Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery.. Clin Neurosurg. 52:29-44.
2004
Gan L, Ye S, Chu A, Anton K, Yi S, Vincent VA, von Schack D, Chin D, Murray J, Lohr S et al..  2004.  Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach.. J Biol Chem. 279(7):5565-72.
2000
Bales KR, Du Y, Holtzman D, Cordell B, Paul SM.  2000.  Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.. Neurobiol Aging. 21(3):427-32;discussion451-3.