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Found 8 results
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Le, David
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A
Tracy TE
,
Sohn PDongmin
,
S Minami S
,
Wang C
,
Min S-W
,
Li Y
,
Zhou Y
,
Le D
,
Lo I
,
Ponnusamy R
et al.
. 2016.
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
.
Neuron. 90(2):245-60.
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
D
Sayed FA
,
Telpoukhovskaia M
,
Kodama L
,
Li Y
,
Zhou Y
,
Le D
,
Hauduc A
,
Ludwig C
,
Gao F
,
Clelland C
et al.
. 2018.
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
.
Proc Natl Acad Sci U S A. 115(40):10172-10177.
Telpoukhovskaia MA
,
Liu K
,
Sayed FA
,
Etchegaray JIker
,
Xie M
,
Zhan L
,
Li Y
,
Zhou Y
,
Le D
,
Bahr BA
et al.
. 2020.
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.
.
Sci Rep. 10(1):13688.
M
Kodama L
,
Guzman E
,
Etchegaray JI
,
Li Y
,
Sayed FA
,
Zhou L
,
Zhou Y
,
Zhan L
,
Le D
,
Udeochu JC
et al.
. 2019.
Microglial microRNAs mediate sex-specific responses to tau pathology.
.
Nat Neurosci.
Krabbe G
,
S Minami S
,
Etchegaray JI
,
Taneja P
,
Djukic B
,
Davalos D
,
Le D
,
Lo I
,
Zhan L
,
Reichert MC
et al.
. 2017.
Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.
.
Proc Natl Acad Sci U S A. 114(19):5029-5034.
P
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
R
S Minami S
,
Shen V
,
Le D
,
Krabbe G
,
Asgarov R
,
Perez-Celajes L
,
Lee C-H
,
Li J
,
Donnelly-Roberts D
,
Gan L
. 2015.
Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
.
Biochem Pharmacol. 97(4):454-462.