Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 13 results
Author [ Title(Desc)] Type Year
Filters: Author is Mok, Sue-Ann  [Clear All Filters]
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A
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MYing, Zhu D, Yu F, Xu J, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. bioRxiv.
Carling GK, Fan L, Foxe NR, Norman K, Wong MYing, Zhu D, Corona C, Razzoli A, Yu F, Yarahmady A et al..  2024.  Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.. Neuron.
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.. bioRxiv.
D
Chen H, Fan L, Guo Q, Wong MYing, Yu F, Foxe N, Wang W, Nessim A, Carling G, Liu B et al..  2023.  DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.. Res Sq.
H
Bravo CParra, Giani AMaria, Perez JMadero, Zhao Z, Samelson A, Wong MYing, Evangelisti A, Fan L, Pozner T, Mercedes M et al..  2023.  Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. bioRxiv.
Bravo CParra, Giani AMaria, Madero-Pérez J, Zhao Z, Wan Y, Samelson AJ, Wong MYing, Evangelisti A, Cordes E, Fan L et al..  2024.  Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. Cell. 187(10):2446-2464.e22.
M
Wang C, Fan L, Khawaja RR, Liu B, Zhan L, Kodama L, Chin M, Li Y, Le D, Zhou Y et al..  2022.  Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.. Nat Commun. 13(1):1969.
P
Sohn PDongmin, Huang CTzu-Ling, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok S-A, Freilich R et al..  2019.  Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.. Neuron.
Chen X, Li Y, Wang C, Tang Y, Mok S-A, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL et al..  2020.  Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.. Mol Neurodegener. 15(1):2.
R
Naguib S, Lopez-Lee C, Torres ERuth, Lee S-I, Zhu J, Zhu D, Ye P, Norman K, Zhao M, Wong MYing et al..  2025.  The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.. Immunity. 58(8):1931-1947.e9.
S
Min S-W, Sohn PDongmin, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok S-A, Gestwicki JE, Gan L.  2018.  SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.. J Neurosci. 38(15):3680-3688.
T
Udeochu JC, Amin S, Huang Y, Fan L, Torres ERuth S, Carling GK, Liu B, McGurran H, Coronas-Samano G, Kauwe G et al..  2023.  Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.. Nat Neurosci. 26(5):737-750.
Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Huttenhain R, Kauwe G et al..  2022.  Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.. Cell. 185(4):712-728.e14.