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A
Bales KR
,
Verina T
,
Cummins DJ
,
Du Y
,
Dodel RC
,
Saura J
,
Fishman CE
,
DeLong CA
,
Piccardo P
,
Petegnief V
et al.
. 1999.
Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 96(26):15233-8.
Holtzman DM
,
Bales KR
,
Tenkova T
,
Fagan AM
,
Parsadanian M
,
Sartorius LJ
,
Mackey B
,
Olney J
,
McKeel D
,
Wozniak D
et al.
. 2000.
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.
.
Proc Natl Acad Sci U S A. 97(6):2892-7.
Koistinaho M
,
Lin S
,
Wu X
,
Esterman M
,
Koger D
,
Hanson J
,
Higgs R
,
Liu F
,
Malkani S
,
Bales KR
et al.
. 2004.
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.
.
Nat Med. 10(7):719-26.
Doyle JP
,
Dougherty JD
,
Heiman M
,
Schmidt EF
,
Stevens TR
,
Ma G
,
Bupp S
,
Shrestha P
,
Shah RD
,
Doughty ML
et al.
. 2008.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
.
Cell. 135(4):749-62.
Grinberg LTenenholz
,
Wang X
,
Wang C
,
Sohn PDongmin
,
Theofilas P
,
Sidhu M
,
Arevalo JBenjamin
,
Heinsen H
,
Huang EJ
,
Rosen H
et al.
. 2013.
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.
.
Acta Neuropathol. 125(4):581-93.
Auclair JR
,
Salisbury JP
,
Johnson JL
,
Petsko GA
,
Ringe D
,
Bosco DA
,
Agar NYR
,
Santagata S
,
Durham HD
,
Agar JN
. 2014.
Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.
.
Proteomics. 14(10):1152-7.
Limbad C
,
Oron TRonnen
,
Alimirah F
,
Davalos AR
,
Tracy TE
,
Gan L
,
Desprez P-Y
,
Campisi J
. 2020.
Astrocyte senescence promotes glutamate toxicity in cortical neurons.
.
PLoS One. 15(1):e0227887.
Barnett D
,
Bohmbach K
,
Grelot V
,
Charlet A
,
Dallérac G
,
Ju YHa
,
Nagai J
,
Orr AG
. 2023.
Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting.
.
J Neurosci. 43(45):7463-7471.
Zimmer TS
,
Orr AL
,
Orr AG
. 2024.
Astrocytes in selective vulnerability to neurodegenerative disease.
.
Trends Neurosci. 47(4):289-302.
Orr AG
,
Hsiao EC
,
Wang MM
,
Ho K
,
Kim DH
,
Wang X
,
Guo W
,
Kang J
,
Yu G-Q
,
Adame A
et al.
. 2015.
Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
.
Nat Neurosci. 18(3):423-34.
Licht-Murava A
,
Meadows SM
,
Palaguachi F
,
Song SC
,
Jackvony S
,
Bram Y
,
Zhou C
,
Schwartz RE
,
Froemke RC
,
Orr AL
et al.
. 2023.
Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.
.
Sci Adv. 9(16):eade1282.
Etherton MR
,
Tabuchi K
,
Sharma M
,
Ko J
,
Südhof TC
. 2011.
An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.
.
EMBO J. 30(14):2908-19.
Amin S
,
Liu B
,
Gan L
. 2023.
Autophagy prevents microglial senescence.
.
Nat Cell Biol. 25(7):923-925.
Naseri N
,
Sharma M
,
Velinov M
. 2020.
Autosomal dominant neuronal ceroid lipofuscinosis: Clinical features and molecular basis.
.
Clin Genet.
B
Reichlin A
,
Hu Y
,
Meffre E
,
Nagaoka H
,
Gong S
,
Kraus M
,
Rajewsky K
,
Nussenzweig MC
. 2001.
B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta.
.
J Exp Med. 193(1):13-23.
Schmidt EF
,
Kus L
,
Gong S
,
Heintz N
. 2013.
BAC transgenic mice and the GENSAT database of engineered mouse strains.
.
Cold Spring Harb Protoc. 2013(3)
Kim U
,
Qin XF
,
Gong S
,
Stevens S
,
Luo Y
,
Nussenzweig M
,
Roeder RG
. 1996.
The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes.
.
Nature. 383(6600):542-7.
McKnight NC
,
Zhong Y
,
Wold MS
,
Gong S
,
Phillips GR
,
Dou Z
,
Zhao Y
,
Heintz N
,
Zong W-X
,
Yue Z
. 2014.
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
.
PLoS Genet. 10(10):e1004626.
Hurtado DE
,
Molina-Porcel L
,
Iba M
,
Aboagye AK
,
Paul SM
,
Trojanowski JQ
,
Lee VM-Y
. 2010.
A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.
.
Am J Pathol. 177(4):1977-88.
Ayed M
,
Lim H
,
Xie L
. 2019.
Biological representation of chemicals using latent target interaction profile.
.
BMC Bioinformatics. 20(Suppl 24):674.
Inoue K
,
Deng Z
,
Chen Y
,
Giannopoulou E
,
Xu R
,
Gong S
,
Greenblatt MB
,
Mangala LS
,
Lopez-Berestein G
,
Kirsch DG
et al.
. 2018.
Bone protection by inhibition of microRNA-182.
.
Nat Commun. 9(1):4108.
Uekawa K
,
Hattori Y
,
Ahn SJi
,
Seo J
,
Casey N
,
Anfray A
,
Zhou P
,
Luo W
,
Anrather J
,
Park L
et al.
. 2023.
Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress.
.
Mol Neurodegener. 18(1):73.
DeMattos RB
,
Bales KR
,
Cummins DJ
,
Paul SM
,
Holtzman DM
. 2002.
Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.
.
Science. 295(5563):2264-7.
Acosta-Ruiz A
,
Gutzeit VA
,
Skelly MJane
,
Meadows S
,
Lee J
,
Parekh P
,
Orr AG
,
Liston C
,
Pleil KE
,
Broichhagen J
et al.
. 2020.
Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo.
.
Neuron. 105(3):446-463.e13.
C
Mukherjee K
,
Sharma M
,
Urlaub H
,
Bourenkov GP
,
Jahn R
,
Südhof TC
,
Wahl MC
. 2008.
CASK Functions as a Mg2+-independent neurexin kinase.
.
Cell. 133(2):328-39.
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