Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 424 results

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

DeMattos RB, O'dell MA, Parsadanian M, Taylor JW, Harmony JAK, Bales KR, Paul SM, Aronow BJ, Holtzman DM. 2002. Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease.. Proc Natl Acad Sci U S A. 99(16):10843-8.

Gan L, Perney TM, Kaczmarek LK. 1996. Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons.. J Biol Chem. 271(10):5859-65.

Bales KR, Tzavara ET, Wu S, Wade MR, Bymaster FP, Paul SM, Nomikos GG. 2006. Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.. J Clin Invest. 116(3):825-32.

Iannone AF, Akgül G, Zhang R, Wacks S, Hussein N, Macias CGinelly, Donatelle A, Bauriedel JMJ, Wright C, Abramov D et al.. 2024. The chemokine Cxcl14 regulates interneuron differentiation in layer I of the somatosensory cortex.. Cell Rep. 43(8):114531.

Pham T-H, Qiu Y, Liu J, Zimmer S, O'Neill E, Xie L, Zhang P. 2022. Chemical-induced gene expression ranking and its application to pancreatic cancer drug repurposing.. Patterns (N Y). 3(4):100441.

Pfau SJ, Langen UH, Fisher TM, Prakash I, Nagpurwala F, Lozoya RA, Lee W-CAllen, Wu Z, Gu C. 2024. Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells.. Nat Neurosci. 27(10):1892-1903.

Benharouga M, Sharma M, Lukacs GL. 2002. CFTR folding and maturation in cells.. Methods Mol Med. 70:229-43.

Burré J, Sharma M. 2022. Cellular And Small Animal Models Of Neurodegenerative Diseases.. J Vis Exp. (186)

Bravo CParra, Naguib SA, Gan L. 2024. Cellular and pathological functions of tau.. Nat Rev Mol Cell Biol. 25(11):845-864.

Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P. 2008. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.. Nat Neurosci. 11(8):932-9.

Gan L, Hahn SJ, Kaczmarek LK. 1999. Cell type-specific expression of the Kv3.1 gene is mediated by a negative element in the 5' untranslated region of the Kv3.1 promoter.. J Neurochem. 73(4):1350-62.

Burré J, Sharma M, Südhof TC. 2018. Cell Biology and Pathophysiology of α-Synuclein.. Cold Spring Harb Perspect Med. 8(3)

Rodriguez-Rodriguez P, Arroyo-Garcia LEnrique, Tsagkogianni C, Li L, Wang W, Végvári Á, Salas-Allende I, Plautz Z, Cedazo-Minguez A, Sinha SC et al.. 2024. A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.. Brain. 147(7):2384-2399.

Wang C, Sun B, Zhou Y, Grubb A, Gan L. 2012. Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.. J Biol Chem. 287(47):39834-41.

Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. 2000. The catalytic pathway of cytochrome p450cam at atomic resolution.. Science. 287(5458):1615-22.

Mukherjee K, Sharma M, Urlaub H, Bourenkov GP, Jahn R, Südhof TC, Wahl MC. 2008. CASK Functions as a Mg2+-independent neurexin kinase.. Cell. 133(2):328-39.

Acosta-Ruiz A, Gutzeit VA, Skelly MJane, Meadows S, Lee J, Parekh P, Orr AG, Liston C, Pleil KE, Broichhagen J et al.. 2020. Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo.. Neuron. 105(3):446-463.e13.

Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung Y-F, Yang Q et al.. 2025. Brain-wide neuronal circuit connectome of human glioblastoma.. Nature. 641(8061):222-231.

DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. 2002. Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.. Science. 295(5563):2264-7.

Uekawa K, Hattori Y, Ahn SJi, Seo J, Casey N, Anfray A, Zhou P, Luo W, Anrather J, Park L et al.. 2023. Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress.. Mol Neurodegener. 18(1):73.

Jati S, Taheri S, Kal S, Sinha SC, Head BP, Mahata SK, Sahoo D. 2025. Boolean Network Modeling Identifies Cognitive Resilience in the First Murine Model of Asymptomatic Alzheimer's Disease.. bioRxiv.

Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, Greenblatt MB, Mangala LS, Lopez-Berestein G, Kirsch DG et al.. 2018. Bone protection by inhibition of microRNA-182.. Nat Commun. 9(1):4108.

Ayed M, Lim H, Xie L. 2019. Biological representation of chemicals using latent target interaction profile.. BMC Bioinformatics. 20(Suppl 24):674.

Hurtado DE, Molina-Porcel L, Iba M, Aboagye AK, Paul SM, Trojanowski JQ, Lee VM-Y. 2010. A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.. Am J Pathol. 177(4):1977-88.

McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong W-X, Yue Z. 2014. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.. PLoS Genet. 10(10):e1004626.