Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 330 results
[ Author(Desc)] Title Type Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
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Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML et al..  2008.  Application of a translational profiling approach for the comparative analysis of CNS cell types.. Cell. 135(4):749-62.
Dräger NM, Sattler SM, Huang CTzu-Ling, Teter OM, Leng K, Hashemi SHadi, Hong J, Aviles G, Clelland CD, Zhan L et al..  2022.  A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.. Nat Neurosci.
Du H, Wong MYing, Zhang T, Santos MNunez, Hsu C, Zhang J, Yu H, Luo W, Hu F.  2021.  A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses.. Life Sci Alliance. 4(7)
Du K, Sharma M, Lukacs GL.  2005.  The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR.. Nat Struct Mol Biol. 12(1):17-25.
E
Edayathumangalam R, Wu R, Garcia R, Wang Y, Wang W, Kreinbring CA, Bach A, Liao J, Stone TA, Terwilliger TC et al..  2013.  Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.. Proc Natl Acad Sci U S A. 110(44):17820-5.
Esposito L, Gan L, Yu G-Q, Essrich C, Mucke L.  2004.  Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.. J Neurochem. 91(6):1260-74.
Etherton MR, Tabuchi K, Sharma M, Ko J, Südhof TC.  2011.  An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.. EMBO J. 30(14):2908-19.
F
Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM.  2002.  Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.. Neurobiol Dis. 9(3):305-18.
Faraco G, Park L, Zhou P, Luo W, Paul SM, Anrather J, Iadecola C.  2016.  Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP.. J Cereb Blood Flow Metab. 36(1):241-52.
Fernandopulle MS, Prestil R, Grunseich C, Wang C, Gan L, Ward ME.  2018.  Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons.. Curr Protoc Cell Biol. 79(1):e51.
Ford BD, Liu Y, Mann MAnne, Krauss R, Phillips K, Gan L, Fischbach GD.  2003.  Neuregulin-1 suppresses muscarinic receptor expression and acetylcholine-activated muscarinic K+ channels in cardiac myocytes.. Biochem Biophys Res Commun. 308(1):23-8.
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Gan L, Hahn SJ, Kaczmarek LK.  1999.  Cell type-specific expression of the Kv3.1 gene is mediated by a negative element in the 5' untranslated region of the Kv3.1 promoter.. J Neurochem. 73(4):1350-62.
Gan L.  2007.  Therapeutic potential of sirtuin-activating compounds in Alzheimer's disease.. Drug News Perspect. 20(4):233-9.
Gan L, Cookson MR, Petrucelli L, La Spada AR.  2018.  Converging pathways in neurodegeneration, from genetics to mechanisms.. Nat Neurosci. 21(10):1300-1309.
Gan L, Kaczmarek LK.  1998.  When, where, and how much? Expression of the Kv3.1 potassium channel in high-frequency firing neurons. J Neurobiol. 37(1):69-79.
Gan L, Mucke L.  2008.  Paths of convergence: sirtuins in aging and neurodegeneration.. Neuron. 58(1):10-4.
Gan L, Anton KE, Masterson BA, Vincent VAM, Ye S, Gonzalez-Zulueta M.  2002.  Specific interference with gene expression and gene function mediated by long dsRNA in neural cells.. J Neurosci Methods. 121(2):151-7.
Gan L, Perney TM, Kaczmarek LK.  1996.  Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons.. J Biol Chem. 271(10):5859-65.
Gan L, Ye S, Chu A, Anton K, Yi S, Vincent VA, von Schack D, Chin D, Murray J, Lohr S et al..  2004.  Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach.. J Biol Chem. 279(7):5565-72.
Georgi B, Craig D, Kember RL, Liu W, Lindquist I, Nasser S, Brown C, Egeland JA, Paul SM, Bućan M.  2014.  Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.. PLoS Genet. 10(3):e1004229.
Ginns EI, St Jean P, Philibert RA, Galdzicka M, Damschroder-Williams P, Thiel B, Long RT, Ingraham LJ, Dalwaldi H, Murray MA et al..  1998.  A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish.. Proc Natl Acad Sci U S A. 95(26):15531-6.
Gong S, Nussenzweig MC.  1996.  Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.. Science. 272(5260):411-4.
Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR.  2007.  Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.. J Neurosci. 27(37):9817-23.
Gong S, Sanchez M, Nussenzweig MC.  1996.  Counterselection against D mu is mediated through immunoglobulin (Ig)alpha-Igbeta.. J Exp Med. 184(6):2079-84.
Gong SC, Lai CF, Dallo S, Esteban M.  1989.  A single point mutation of Ala-25 to Asp in the 14,000-Mr envelope protein of vaccinia virus induces a size change that leads to the small plaque size phenotype of the virus.. J Virol. 63(11):4507-14.