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L
Lopez-Lee C
,
Kodama L
,
Fan L
,
Zhu D
,
Zhu J
,
Wong MYing
,
Ye P
,
Norman K
,
Foxe NR
,
Ijaz L
et al.
. 2024.
Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.
.
Science. 386(6725):eadk7844.
Lopez-Lee C
,
Torres ERuth S
,
Carling G
,
Gan L
. 2024.
Mechanisms of sex differences in Alzheimer's disease.
.
Neuron.
Luo W
,
Ip FCF
,
Fu G
,
Cheung K
,
Tian Y
,
Hu Y
,
Sinha A
,
Cheng EYL
,
Wu X
,
Bustos V
et al.
. 2020.
A Pentacyclic Triterpene from Targets γ-Secretase.
.
ACS Chem Neurosci. 11(18):2827-2835.
Luo W
,
Qu W
,
Gan L
. 2023.
The AD odyssey 2023: Tales of single cell.
.
Cell. 186(20):4257-4259.
Luo W-jie
,
Wang H
,
Li H
,
Kim BS
,
Shah S
,
Lee H-J
,
Thinakaran G
,
Kim T-W
,
Yu G
,
Xu H
. 2003.
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.
.
J Biol Chem. 278(10):7850-4.
Luo W
,
Dou F
,
Rodina A
,
Chip S
,
Kim J
,
Zhao Q
,
Moulick K
,
Aguirre J
,
Wu N
,
Greengard P
et al.
. 2007.
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
.
Proc Natl Acad Sci U S A. 104(22):9511-6.
Luo P
,
Yang F
,
Li J
,
Niemeyer JE
,
Zhan F
,
Estin J
,
Zhao M
,
Li D
,
Lin W
,
Liou J-Y
et al.
. 2023.
Excitatory-inhibitory mismatch shapes node recruitment in an epileptic network.
.
Epilepsia. 64(7):1939-1950.
Luo W
,
Liu W
,
Hu X
,
Hanna M
,
Caravaca A
,
Paul SM
. 2015.
Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.
.
Sci Rep. 5:11161.
M
Majewska MD
,
Harrison NL
,
Schwartz RD
,
Barker JL
,
Paul SM
. 1986.
Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor.
.
Science. 232(4753):1004-7.
Mannaioni G
,
Orr AG
,
Hamill CE
,
Yuan H
,
Pedone KH
,
McCoy KL
,
Palmini RBerlinguer
,
Junge CE
,
C Lee J
,
Yepes M
et al.
. 2008.
Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1.
.
J Biol Chem. 283(29):20600-11.
Martens LHerl
,
Zhang J
,
Barmada SJ
,
Zhou P
,
Kamiya S
,
Sun B
,
Min S-W
,
Gan L
,
Finkbeiner S
,
Huang EJ
et al.
. 2012.
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
.
J Clin Invest. 122(11):3955-9.
Martinez-Losa M
,
Tracy TE
,
Ma K
,
Verret L
,
Clemente-Perez A
,
Khan AS
,
Cobos I
,
Ho K
,
Gan L
,
Mucke L
et al.
. 2018.
Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease.
.
Neuron. 98(1):75-89.e5.
Mastroberardino PG
,
Orr AL
,
Hu X
,
Na HMee
,
J Greenamyre T
. 2008.
A FRET-based method to study protein thiol oxidation in histological preparations.
.
Free Radic Biol Med. 45(7):971-81.
Mattos C
,
Bellamacina CR
,
Peisach E
,
Pereira A
,
Vitkup D
,
Petsko GA
,
Ringe D
. 2006.
Multiple solvent crystal structures: probing binding sites, plasticity and hydration.
.
J Mol Biol. 357(5):1471-82.
McKnight NC
,
Zhong Y
,
Wold MS
,
Gong S
,
Phillips GR
,
Dou Z
,
Zhao Y
,
Heintz N
,
Zong W-X
,
Yue Z
. 2014.
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
.
PLoS Genet. 10(10):e1004626.
Meadows SM
,
Palaguachi F
,
Jang MWendy
,
Licht-Murava A
,
Barnett D
,
Zimmer TS
,
Zhou C
,
McDonough SR
,
Orr AL
,
Orr AG
. 2024.
Hippocampal astrocytes induce sex-dimorphic effects on memory.
.
Cell Rep. 43(6):114278.
Mecozzi VJ
,
Berman DE
,
Simoes S
,
Vetanovetz C
,
Awal MR
,
Patel VM
,
Schneider RT
,
Petsko GA
,
Ringe D
,
Small SA
. 2014.
Pharmacological chaperones stabilize retromer to limit APP processing.
.
Nat Chem Biol. 10(6):443-9.
Medrihan L
,
Umschweif G
,
Sinha A
,
Reed S
,
Lee J
,
Gindinova K
,
Sinha SC
,
Greengard P
,
Sagi Y
. 2020.
Reduced Kv3.1 Activity in Dentate Gyrus Parvalbumin Cells Induces Vulnerability to Depression.
.
Biol Psychiatry. 88(5):405-414.
Min S-W
,
Cho S-H
,
Zhou Y
,
Schroeder S
,
Haroutunian V
,
Seeley WW
,
Huang EJ
,
Shen Y
,
Masliah E
,
Mukherjee C
et al.
. 2010.
Acetylation of tau inhibits its degradation and contributes to tauopathy.
.
Neuron. 67(6):953-66.
Min S-W
,
Sohn PD
,
Cho S-H
,
Swanson RA
,
Gan L
. 2013.
Sirtuins in neurodegenerative diseases: an update on potential mechanisms.
.
Front Aging Neurosci. 5:53.
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
Min S-W
,
Sohn PDongmin
,
Li Y
,
Devidze N
,
Johnson JR
,
Krogan NJ
,
Masliah E
,
Mok S-A
,
Gestwicki JE
,
Gan L
. 2018.
SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.
.
J Neurosci. 38(15):3680-3688.
S Minami S
,
Min S-W
,
Krabbe G
,
Wang C
,
Zhou Y
,
Asgarov R
,
Li Y
,
Martens LH
,
Elia LP
,
Ward ME
et al.
. 2014.
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
.
Nat Med. 20(10):1157-64.
S Minami S
,
Shen V
,
Le D
,
Krabbe G
,
Asgarov R
,
Perez-Celajes L
,
Lee C-H
,
Li J
,
Donnelly-Roberts D
,
Gan L
. 2015.
Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
.
Biochem Pharmacol. 97(4):454-462.
S Minami S
,
Sun B
,
Popat K
,
Kauppinen T
,
Pleiss M
,
Zhou Y
,
Ward ME
,
Floreancig P
,
Mucke L
,
Desai T
et al.
. 2012.
Selective targeting of microglia by quantum dots.
.
J Neuroinflammation. 9:22.
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