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News & Events


Upcoming seminar and event information

Dr. Wenjie Luo

Congratulations! New R01 from NIH awarded to Dr. Wenjie Luo

DAP12 (also called TYROBP) acts as an adaptor protein in microglia involved in the cross-interaction of signaling networks of microglial surface immune receptors, including AD risk gene TREM2. DAP12 has been implicated as a central player in an AD-associated microglia specific module. Dr. Luo will investigate the functions of DAP12 in regulating microglia-mediated tau metabolism and inflammation and dissect the molecular and cellular mechanism underpinning these activities.

Dr. Anna and Adam Orr

Congratulations! New R01 from NIH Awarded to Dr. Anna Orr

TDP-43 is a nucleic acid-binding protein linked to neurodegenerative disorders, but its roles in non-neuronal cells like astrocytes are poorly understood. The proposed research will examine how astrocytic TDP-43 affects glial-neuronal interactions and cognitive impairments. These studies will unravel novel intracellular and intercellular molecular mechanisms underlying cognitive deficits in neurodegenerative disease and may reveal promising therapeutic strategies for TDP-43-related pathology...

Debra Abramov

Congratulations! Debra Abramov from Burré lab has received a NRSA F30 fellowship from the NICHD

Debra Abramov from the Burré Lab has received a NRSA F30 fellowship from the NICHD, to investigate how Munc18-1 mutations disrupt syntaxin-5 stability and general secretory trafficking.

Despite a known genetic cause, no effective treatments exist for Munc18-1 related disorders, which cause intractable epilepsy, severe intellectual disability, and other severe neurologic symptoms in children. The aim of my proposal is to investigate the non-synaptic neuronal deficits that are caused by...

Weill Cornell Medicine Helen & Robert Appel Alzheimer’s Disease Research Institute 413 E. 69th St. New York, NY 10021