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Upcoming seminar and event information

Appel Alzheimer's Disease Research Institute Symposium

The Eighth Annual Appel Alzheimer's Disease Research Institute Symposium is scheduled virtually on Wednesday, October 14th, 2020

The Eighth Annual Appel Alzheimer's Disease Research Institute Symposium is scheduled virtually on Wednesday, October 14th, 2020 from 1:00PM - 2:30PM.

This is an outstanding annual event hosted by Dean Choi, Appel Alzheimer's Institute and the Feil Family BMRI. Dr. Li Gan, Director of the Appel Institute will open the symposium, followed by four cutting edge scientific presentations by Dr. Jonathan...

Dr. Anna and Adam Orr

Congratulations! Second R01 from the NIH Awarded to Dr. Anna Orr’s team

Mitochondria are organelles that produce energy and participate in normal intracellular signaling. However, they also release free radicals that can impair neural cells and promote disorders of the brain. The main contributing factors in dementia, including aging and proteinopathy, are linked to mitochondrial dysfunction and accumulation of free radicals. Recent evidence suggests that mitochondrial free radicals act as central drivers of diverse pathogenic processes in dementia. Dr. Orr’s...

Dr. Wenjie Luo

Congratulations! New R01 from NIH awarded to Dr. Wenjie Luo

DAP12 (also called TYROBP) acts as an adaptor protein in microglia involved in the cross-interaction of signaling networks of microglial surface immune receptors, including AD risk gene TREM2. DAP12 has been implicated as a central player in an AD-associated microglia specific module. Dr. Luo will investigate the functions of DAP12 in regulating microglia-mediated tau metabolism and inflammation and dissect the molecular and cellular mechanism underpinning these activities.

Weill Cornell Medicine Helen & Robert Appel Alzheimer’s Disease Research Institute 413 E. 69th St. New York, NY 10021