News

Appel Poster Symposium 2024

Exciting news from the Appel Institute! We recently hosted our second Poster Symposium at the prestigious Griffin Faculty Club, providing an incredible venue for our event. The level of participation was exceptional, with 33 posters submitted by diverse labs within Appel.

The symposium showcased an array of fascinating projects spanning various fields, including neuroscience, neurodegeneration, machine learning, artificial intelligence, glial biology, and drug discovery. Attendees had...

Li Gan

Honoring Dr. Li Gan: Recipient of The Jessica M. and Natan Bibliowicz Award for Excellence in Mentorship

Professor in Neurodegenerative Diseases and director of the Helen and Robert Appel Alzheimer’s Disease Research Institute at Weill Cornell Medicine, received the Jessica M. And Natan Bibliowicz Award in recognition of her scientific achievements and mentorship of faculty. As one of her mentees said, “Dr. Gan is a role model who leads with integrity, fosters collaboration and encourages excellence.”

“This award reflects the importance of supporting the next...

Wenhui Qu

Celebrating Wenhui Qu's Achievement: Bright Focus Postdoctoral Fellowship Award!

Tauopathies, including Alzheimer's disease (AD), involve the abnormal accumulation of the toxic Tau protein in neurons, affecting millions of people without a cure. Our lab has pioneered modeling Tau buildup in human neurons using stem cells. This study proposes transplanting human stem cells into mouse brains to generate a novel chimera human-mouse model that develops Tau accumulation. Using this model, our research also examines how specific molecular pathways might affect the...

Sadaf

Sadaf Amin, PhD Promoted to Instructor in Neuroscience at WCM

We are thrilled to announce that Sadaf Amin, PhD, has been promoted to the role of Instructor in Neuroscience at WCM. This promotion is a testament to her exceptional dedication and expertise in the field.

Neuron_review

Neuron review: sex differences

The Neuron review by Lopez-Lee and Torres et al. at Gan lab addresses how sex-specific factors influence Alzheimer's disease (AD) progression. It suggests that hormones and chromosomes may affect aging-related processes like inflammation, metabolism, and autophagy, leading to different AD patterns in men and women. By synthesizing advanced research, including single-cell RNA sequencing and omics analyses, the review highlights the significant role sex plays in AD prevalence, pathology...

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