Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 137 results
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Cho S-H, Chen JA, Sayed F, Ward ME, Gao F, Nguyen TA, Krabbe G, Sohn PDongmin, Lo I, Minami S et al..  2015.  SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.. J Neurosci. 35(2):807-18.
Das C, Hoang QQ, Kreinbring CA, Luchansky SJ, Meray RK, Ray SS, Lansbury PT, Ringe D, Petsko GA.  2006.  Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.. Proc Natl Acad Sci U S A. 103(12):4675-80.
Auclair JR, Brodkin HR, J D'Aquino A, Petsko GA, Ringe D, Agar JN.  2013.  Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase.. Biochemistry. 52(36):6145-50.
Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RLS et al..  2015.  Suppressors of superoxide production from mitochondrial complex III.. Nat Chem Biol. 11(11):834-6.
Brand MD, Goncalves RLS, Orr AL, Vargas L, Gerencser AA, Jensen MBorch, Wang YT, Melov S, Turk CN, Matzen JT et al..  2016.  Suppressors of Superoxide-HO Production at Site I of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.. Cell Metab. 24(4):582-592.
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Abramov D, Guiberson NGuy Lewis, Daab A, Na Y, Petsko GA, Sharma M, Burré J.  2020.  Targeted stabilization of Munc18-1 function via pharmacological chaperones.. EMBO Mol Med. :e12354.
Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR.  2007.  Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs.. J Neurosci. 27(37):9817-23.
Heymont J, Berenfeld L, Collins J, Kaganovich A, Maynes B, Moulin A, Ratskovskaya I, Poon PP, Johnston GC, Kamenetsky M et al..  2000.  TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation.. Proc Natl Acad Sci U S A. 97(23):12672-7.
de Haas R, Heltzel LCMW, Tax D, van den Broek P, Steenbreker H, Verheij MMM, Russel FGM, Orr AL, Nakamura K, Smeitink JAM.  2019.  To be or not to be pink(1): contradictory findings in an animal model for Parkinson's disease.. Brain Commun. 1(1):fcz016.
Kim KHye, Liu J, Galvin RJSells, Dage JL, Egeland JA, Smith RC, Merchant KM, Paul SM.  2015.  Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.. PLoS One. 10(11):e0142693.
Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, D Surmeier J et al..  2008.  A translational profiling approach for the molecular characterization of CNS cell types.. Cell. 135(4):738-48.
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Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH, Lindquist S et al..  2011.  A yeast model of FUS/TLS-dependent cytotoxicity.. PLoS Biol. 9(4):e1001052.