Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 137 results
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Journal Article
S Minami S, Shen V, Le D, Krabbe G, Asgarov R, Perez-Celajes L, Lee C-H, Li J, Donnelly-Roberts D, Gan L.  2015.  Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.. Biochem Pharmacol. 97(4):454-462.
Shin M-K, Vázquez-Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón-Pérez CJ, Barker S, Miller E, Franke K, Noterman MF et al..  2021.  Reducing acetylated tau is neuroprotective in brain injury.. Cell.
Witten IB, Steinberg EE, Lee SYeun, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C et al..  2011.  Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.. Neuron. 72(5):721-33.
Witten IB, Steinberg EE, Lee SYeun, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C et al..  2011.  Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.. Neuron. 72(5):721-33.
Kumar S, Singh SKumar, Viswakarma N, Sondarva G, Nair RSathish, Sethupathi P, Dorman M, Sinha SC, Hoskins K, Thatcher G et al..  2020.  Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8 T cells.. J Immunother Cancer. 8(2)
A Willsey J, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA et al..  2018.  The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.. Cell. 174(3):505-520.
A Willsey J, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA et al..  2018.  The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.. Cell. 174(3):505-520.
A Willsey J, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA et al..  2018.  The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.. Cell. 174(3):505-520.
Zhan L, Krabbe G, Du F, Jones I, Reichert MC, Telpoukhovskaia M, Kodama L, Wang C, Cho S-H, Sayed F et al..  2019.  Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.. PLoS Biol. 17(2):e3000134.
Burré J, Vivona S, Diao J, Sharma M, Brunger AT, Südhof TC.  2013.  Properties of native brain α-synuclein.. Nature. 498(7453):E4-6;discussionE6-7.
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RLA, Kim J, May J, Tocilescu MAleksandra, Liu W, Ko HSeok et al..  2010.  PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.. Proc Natl Acad Sci U S A. 107(1):378-83.
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RLA, Kim J, May J, Tocilescu MAleksandra, Liu W, Ko HSeok et al..  2010.  PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.. Proc Natl Acad Sci U S A. 107(1):378-83.
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RLA, Kim J, May J, Tocilescu MAleksandra, Liu W, Ko HSeok et al..  2010.  PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.. Proc Natl Acad Sci U S A. 107(1):378-83.
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM.  2001.  Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.. Proc Natl Acad Sci U S A. 98(15):8850-5.
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM.  2001.  Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.. Proc Natl Acad Sci U S A. 98(15):8850-5.
Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MBukar, Clelland CD, Cohen AD, Crary JF, Dage JL et al..  2024.  Novel avenues of tau research.. Alzheimers Dement.
Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MBukar, Clelland CD, Cohen AD, Crary JF, Dage JL et al..  2024.  Novel avenues of tau research.. Alzheimers Dement.
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK et al..  2022.  Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.. Mol Neurodegener. 17(1):41.
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK et al..  2022.  Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.. Mol Neurodegener. 17(1):41.
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK et al..  2022.  Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.. Mol Neurodegener. 17(1):41.
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK et al..  2022.  Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.. Mol Neurodegener. 17(1):41.
Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R.  2013.  NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.. Neurosci Lett. 547:16-20.
Bales KR, Du Y, Dodel RC, Yan GM, Hamilton-Byrd E, Paul SM.  1998.  The NF-kappaB/Rel family of proteins mediates Abeta-induced neurotoxicity and glial activation.. Brain Res Mol Brain Res. 57(1):63-72.
Bales KR, Du Y, Dodel RC, Yan GM, Hamilton-Byrd E, Paul SM.  1998.  The NF-kappaB/Rel family of proteins mediates Abeta-induced neurotoxicity and glial activation.. Brain Res Mol Brain Res. 57(1):63-72.
Lai Y, Zhao C, Tian Z, Wang C, Fan J, Hu X, Tu J, Li T, Leitz J, Pfuetzner RA et al..  2023.  Neutral lysophosphatidylcholine mediates α-synuclein-induced synaptic vesicle clustering.. Proc Natl Acad Sci U S A. 120(44):e2310174120.