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2017
Wang C
,
Ward ME
,
Chen R
,
Liu K
,
Tracy TE
,
Chen X
,
Xie M
,
Sohn PDongmin
,
Ludwig C
,
Meyer-Franke A
et al.
. 2017.
Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.
.
Stem Cell Reports. 9(4):1221-1233.
2016
Möller T
,
Bard F
,
Bhattacharya A
,
Biber K
,
Campbell B
,
Dale E
,
Eder C
,
Gan L
,
Garden GA
,
Hughes ZA
et al.
. 2016.
Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.
.
Glia. 64(10):1788-94.
Brand MD
,
Goncalves RLS
,
Orr AL
,
Vargas L
,
Gerencser AA
,
Jensen MBorch
,
Wang YT
,
Melov S
,
Turk CN
,
Matzen JT
et al.
. 2016.
Suppressors of Superoxide-HO Production at Site I of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
.
Cell Metab. 24(4):582-592.
2015
Orr AG
,
Hsiao EC
,
Wang MM
,
Ho K
,
Kim DH
,
Wang X
,
Guo W
,
Kang J
,
Yu G-Q
,
Adame A
et al.
. 2015.
Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
.
Nat Neurosci. 18(3):423-34.
Orr AG
,
Hsiao EC
,
Wang MM
,
Ho K
,
Kim DH
,
Wang X
,
Guo W
,
Kang J
,
Yu G-Q
,
Adame A
et al.
. 2015.
Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
.
Nat Neurosci. 18(3):423-34.
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
S Minami S
,
Shen V
,
Le D
,
Krabbe G
,
Asgarov R
,
Perez-Celajes L
,
Lee C-H
,
Li J
,
Donnelly-Roberts D
,
Gan L
. 2015.
Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
.
Biochem Pharmacol. 97(4):454-462.
Cho S-H
,
Chen JA
,
Sayed F
,
Ward ME
,
Gao F
,
Nguyen TA
,
Krabbe G
,
Sohn PDongmin
,
Lo I
,
Minami S
et al.
. 2015.
SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.
.
J Neurosci. 35(2):807-18.
Orr AL
,
Vargas L
,
Turk CN
,
Baaten JE
,
Matzen JT
,
Dardov VJ
,
Attle SJ
,
Li J
,
Quackenbush DC
,
Goncalves RLS
et al.
. 2015.
Suppressors of superoxide production from mitochondrial complex III.
.
Nat Chem Biol. 11(11):834-6.
Kim KHye
,
Liu J
,
Galvin RJSells
,
Dage JL
,
Egeland JA
,
Smith RC
,
Merchant KM
,
Paul SM
. 2015.
Transcriptomic Analysis of Induced Pluripotent Stem Cells Derived from Patients with Bipolar Disorder from an Old Order Amish Pedigree.
.
PLoS One. 10(11):e0142693.
2014
Fargo KN
,
Aisen P
,
Albert M
,
Au R
,
Corrada MM
,
DeKosky S
,
Drachman D
,
Fillit H
,
Gitlin L
,
Haas M
et al.
. 2014.
2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.
.
Alzheimers Dement. 10(5 Suppl):S430-52.
Fargo KN
,
Aisen P
,
Albert M
,
Au R
,
Corrada MM
,
DeKosky S
,
Drachman D
,
Fillit H
,
Gitlin L
,
Haas M
et al.
. 2014.
2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.
.
Alzheimers Dement. 10(5 Suppl):S430-52.
Auclair JR
,
Salisbury JP
,
Johnson JL
,
Petsko GA
,
Ringe D
,
Bosco DA
,
Agar NYR
,
Santagata S
,
Durham HD
,
Agar JN
. 2014.
Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.
.
Proteomics. 14(10):1152-7.
McKnight NC
,
Zhong Y
,
Wold MS
,
Gong S
,
Phillips GR
,
Dou Z
,
Zhao Y
,
Heintz N
,
Zong W-X
,
Yue Z
. 2014.
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
.
PLoS Genet. 10(10):e1004626.
Linsenbardt AJ
,
Taylor A
,
Emnett CM
,
Doherty JJ
,
Krishnan K
,
Covey DF
,
Paul SM
,
Zorumski CF
,
Mennerick S
. 2014.
Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.
.
Neuropharmacology. 85:232-42.
2013
Steele JW
,
Lachenmayer ML
,
Ju S
,
Stock A
,
Liken J
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.
.
Mol Psychiatry. 18(8):889-97.
Steele JW
,
Lachenmayer ML
,
Ju S
,
Stock A
,
Liken J
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.
.
Mol Psychiatry. 18(8):889-97.
Steele JW
,
Ju S
,
Lachenmayer ML
,
Liken J
,
Stock A
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.
.
Mol Psychiatry. 18(8):882-8.
Steele JW
,
Ju S
,
Lachenmayer ML
,
Liken J
,
Stock A
,
Kim SH
,
Delgado LM
,
Alfaro IE
,
Bernales S
,
Verdile G
et al.
. 2013.
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.
.
Mol Psychiatry. 18(8):882-8.
Paul SM
,
Doherty JJ
,
Robichaud AJ
,
Belfort GM
,
Chow BY
,
Hammond RS
,
Crawford DC
,
Linsenbardt AJ
,
Shu H-J
,
Izumi Y
et al.
. 2013.
The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors.
.
J Neurosci. 33(44):17290-300.
Diao J
,
Burré J
,
Vivona S
,
Cipriano DJ
,
Sharma M
,
Kyoung M
,
Südhof TC
,
Brunger AT
. 2013.
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2.
.
Elife. 2:e00592.
Pranski E
,
Van Sanford CD
,
Dalal N
,
Orr AL
,
Karmali D
,
Cooper DS
,
Gearing M
,
Lah JJ
,
Levey AI
,
Betarbet R
. 2013.
NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.
.
Neurosci Lett. 547:16-20.
Burré J
,
Vivona S
,
Diao J
,
Sharma M
,
Brunger AT
,
Südhof TC
. 2013.
Properties of native brain α-synuclein.
.
Nature. 498(7453):E4-6;discussionE6-7.
Auclair JR
,
Brodkin HR
,
J D'Aquino A
,
Petsko GA
,
Ringe D
,
Agar JN
. 2013.
Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase.
.
Biochemistry. 52(36):6145-50.
2012
Davies CW
,
Chaney J
,
Korbel G
,
Ringe D
,
Petsko GA
,
Ploegh H
,
Das C
. 2012.
The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK).
.
Bioorg Med Chem Lett. 22(12):3900-4.
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