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Found 173 results
Author
Title
Type
[
Year
]
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is
K
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2020
Kumar S
,
Singh SKumar
,
Viswakarma N
,
Sondarva G
,
Nair RSathish
,
Sethupathi P
,
Sinha SC
,
Emmadi R
,
Hoskins K
,
Danciu O
et al.
. 2020.
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
.
Proc Natl Acad Sci U S A. 117(14):7961-7970.
Zhu PK
,
W Zheng S
,
Zhang P
,
Jing M
,
Borden PM
,
Ali F
,
Guo K
,
Feng J
,
Marvin JS
,
Wang Y
et al.
. 2020.
Nanoscopic Visualization of Restricted Nonvolume Cholinergic and Monoaminergic Transmission with Genetically Encoded Sensors.
.
Nano Lett. 20(6):4073-4083.
Chen X
,
Li Y
,
Wang C
,
Tang Y
,
Mok S-A
,
Tsai RM
,
Rojas JC
,
Karydas A
,
Miller BL
,
Boxer AL
et al.
. 2020.
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.
.
Mol Neurodegener. 15(1):2.
Kumar S
,
Singh SKumar
,
Viswakarma N
,
Sondarva G
,
Nair RSathish
,
Sethupathi P
,
Dorman M
,
Sinha SC
,
Hoskins K
,
Thatcher G
et al.
. 2020.
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8 T cells.
.
J Immunother Cancer. 8(2)
2021
Caballero B
,
Bourdenx M
,
Luengo E
,
Diaz A
,
Sohn PDongmin
,
Chen X
,
Wang C
,
Juste YR
,
Wegmann S
,
Patel B
et al.
. 2021.
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
.
Nat Commun. 12(1):2238.
Caballero B
,
Bourdenx M
,
Luengo E
,
Diaz A
,
Sohn PDongmin
,
Chen X
,
Wang C
,
Juste YR
,
Wegmann S
,
Patel B
et al.
. 2021.
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
.
Nat Commun. 12(1):2238.
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
Singh SKumar
,
Kumar S
,
Viswakarma N
,
Principe DR
,
Das S
,
Sondarva G
,
Nair RSathish
,
Srivastava P
,
Sinha SC
,
Grippo PJ
et al.
. 2021.
MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3.
.
Oncogene. 40(43):6153-6165.
Viswakarma N
,
Sondarva G
,
Principe DR
,
Nair RSathish
,
Kumar S
,
Singh SKumar
,
Das S
,
Sinha SC
,
Grippo PJ
,
Grimaldo S
et al.
. 2021.
Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development.
.
Cancer Lett. 515:1-13.
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
Shin M-K
,
Vázquez-Rosa E
,
Koh Y
,
Dhar M
,
Chaubey K
,
Cintrón-Pérez CJ
,
Barker S
,
Miller E
,
Franke K
,
Noterman MF
et al.
. 2021.
Reducing acetylated tau is neuroprotective in brain injury.
.
Cell.
Lopez-Lee C
,
Kodama L
,
Gan L
. 2021.
Sex Differences in Neurodegeneration: The Role of the Immune System in Humans.
.
Biol Psychiatry.
2022
Dräger NM
,
Sattler SM
,
Huang CTzu-Ling
,
Teter OM
,
Leng K
,
Hashemi SHadi
,
Hong J
,
Aviles G
,
Clelland CD
,
Zhan L
et al.
. 2022.
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
.
Nat Neurosci.
Dräger NM
,
Sattler SM
,
Huang CTzu-Ling
,
Teter OM
,
Leng K
,
Hashemi SHadi
,
Hong J
,
Aviles G
,
Clelland CD
,
Zhan L
et al.
. 2022.
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
.
Nat Neurosci.
Xie YXue
,
Naseri NN
,
Fels J
,
Kharel P
,
Na Y
,
Lane D
,
Burré J
,
Sharma M
. 2022.
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
.
Nat Commun. 13(1):4918.
Wang C
,
Fan L
,
Khawaja RR
,
Liu B
,
Zhan L
,
Kodama L
,
Chin M
,
Li Y
,
Le D
,
Zhou Y
et al.
. 2022.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
.
Nat Commun. 13(1):1969.
Wang C
,
Fan L
,
Khawaja RR
,
Liu B
,
Zhan L
,
Kodama L
,
Chin M
,
Li Y
,
Le D
,
Zhou Y
et al.
. 2022.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
.
Nat Commun. 13(1):1969.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Kuo S-H
,
Tasset I
,
Cheng MM
,
Diaz A
,
Pan M-K
,
Lieberman OJ
,
Hutten SJ
,
Alcalay RN
,
Kim S
,
Ximénez-Embún P
et al.
. 2022.
Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy.
.
Sci Adv. 8(6):eabm6393.
Xia D
,
Lianoglou S
,
Sandmann T
,
Calvert M
,
Suh JH
,
Thomsen E
,
Dugas J
,
Pizzo ME
,
DeVos SL
,
Earr TK
et al.
. 2022.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
.
Mol Neurodegener. 17(1):41.
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