Publications

Found 51 results

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2024

Bravo CParra, Giani AMaria, Madero-Pérez J, Zhao Z, Wan Y, Samelson AJ, Wong MYing, Evangelisti A, Cordes E, Fan L et al.. 2024. Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. Cell. 187(10):2446-2464.e22.

Burré J, Edwards RH, Halliday G, Lang AE, Lashuel HA, Melki R, Murayama S, Outeiro TF, Papa SM, Stefanis L et al.. 2024. Research Priorities on the Role of α-Synuclein in Parkinson's Disease Pathogenesis.. Mov Disord. 39(10):1663-1678.

2023

Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Goodness D, Tian R, Grosjean P, Abskharon R, Eisenberg D et al.. 2023. CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. bioRxiv.

Luo P, Yang F, Li J, Niemeyer JE, Zhan F, Estin J, Zhao M, Li D, Lin W, Liou J-Y et al.. 2023. Excitatory-inhibitory mismatch shapes node recruitment in an epileptic network.. Epilepsia. 64(7):1939-1950.

Yang X, Wen J, Yang H, Jones IR, Zhu X, Liu W, Li B, Clelland CD, Luo W, Wong MYing et al.. 2023. Functional characterization of Alzheimer's disease genetic variants in microglia.. Nat Genet. 55(10):1735-1744.

Bravo CParra, Giani AMaria, Perez JMadero, Zhao Z, Samelson A, Wong MYing, Evangelisti A, Fan L, Pozner T, Mercedes M et al.. 2023. Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.. bioRxiv.

Evering TH, Marston JL, Gan L, Nixon DF. 2023. Transposable elements and Alzheimer's disease pathogenesis.. Trends Neurosci. 46(3):170-172.

2022

Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK et al.. 2022. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.. Mol Neurodegener. 17(1):41.

Carnazza KE, Komer LE, Xie YXue, Pineda A, Briano JAntonio, Gao V, Na Y, Ramlall T, Buchman VL, Eliezer D et al.. 2022. Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins.. Cell Rep. 39(2):110675.

2020

Naseri NN, Ergel B, Kharel P, Na Y, Huang Q, Huang R, Dolzhanskaya N, Burré J, Velinov MT, Sharma M. 2020. Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.. Nat Struct Mol Biol. 27(2):192-201.

Telpoukhovskaia MA, Liu K, Sayed FA, Etchegaray JIker, Xie M, Zhan L, Li Y, Zhou Y, Le D, Bahr BA et al.. 2020. Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.. Sci Rep. 10(1):13688.

Inda MCarmen, Joshi S, Wang T, Bolaender A, Gandu S, Iii JKoren, Che AYue, Taldone T, Yan P, Sun W et al.. 2020. The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.. Nat Commun. 11(1):319.

Kumar S, Singh SKumar, Viswakarma N, Sondarva G, Nair RSathish, Sethupathi P, Sinha SC, Emmadi R, Hoskins K, Danciu O et al.. 2020. Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.. Proc Natl Acad Sci U S A. 117(14):7961-7970.

2019

Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC et al.. 2019. Microglial microRNAs mediate sex-specific responses to tau pathology.. Nat Neurosci.

2017

Cao J, Gaamouch FEl, Meabon JS, Meeker KD, Zhu L, Zhong MB, Bendik J, Elder G, Jing P, Xia J et al.. 2017. ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.. Sci Rep. 7(1):11372.

Boselli M, Lee B-H, Robert J, Prado MA, Min S-W, Cheng C, M Silva C, Seong C, Elsasser S, Hatle KM et al.. 2017. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.. J Biol Chem. 292(47):19209-19225.

Pathak D, Berthet A, Bendor JT, Yu K, Sellnow RC, Orr AL, Nguyen MK, Edwards RH, Manfredsson FP, Nakamura K. 2017. Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons.. eNeuro. 4(2)

Krabbe G, S Minami S, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC et al.. 2017. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.. Proc Natl Acad Sci U S A. 114(19):5029-5034.

2016

Tracy TE, Sohn PDongmin, S Minami S, Wang C, Min S-W, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R et al.. 2016. Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.. Neuron. 90(2):245-60.

Möller T, Bard F, Bhattacharya A, Biber K, Campbell B, Dale E, Eder C, Gan L, Garden GA, Hughes ZA et al.. 2016. Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.. Glia. 64(10):1788-94.

2015

Min S-W, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, S Minami S, Defensor E, Mok SAnn et al.. 2015. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.. Nat Med. 21(10):1154-62.

2014

Linsenbardt AJ, Taylor A, Emnett CM, Doherty JJ, Krishnan K, Covey DF, Paul SM, Zorumski CF, Mennerick S. 2014. Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.. Neuropharmacology. 85:232-42.

Georgi B, Craig D, Kember RL, Liu W, Lindquist I, Nasser S, Brown C, Egeland JA, Paul SM, Bućan M. 2014. Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.. PLoS Genet. 10(3):e1004229.

S Minami S, Min S-W, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME et al.. 2014. Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.. Nat Med. 20(10):1157-64.