Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 376 results

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2005

X Yang W, Gong S. 2005. An overview on the generation of BAC transgenic mice for neuroscience research.. Curr Protoc Neurosci. Chapter 5:Unit5.20.

Gu X, Li C, Wei W, Lo V, Gong S, Li S-H, Iwasato T, Itohara S, Li X-J, Mody I et al.. 2005. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.. Neuron. 46(3):433-44.

Gu X, Li C, Wei W, Lo V, Gong S, Li S-H, Iwasato T, Itohara S, Li X-J, Mody I et al.. 2005. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.. Neuron. 46(3):433-44.

Kaczmarek LK, Bhattacharjee A, Desai R, Gan L, Song P, von Hehn CAA, Whim MD, Yang B. 2005. Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels.. Hear Res. 206(1-2):133-45.

Chen J, Zhou Y, Mueller-Steiner S, Chen L-F, Kwon H, Yi S, Mucke L, Gan L. 2005. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.. J Biol Chem. 280(48):40364-74.

Hamill CE, Goldshmidt A, Nicole O, McKeon RJ, Brat DJ, Traynelis SF. 2005. Special lecture: glial reactivity after damage: implications for scar formation and neuronal recovery.. Clin Neurosurg. 52:29-44.

2004

Sparwasser T, Gong S, Li JYH, Eberl G. 2004. General method for the modification of different BAC types and the rapid generation of BAC transgenic mice.. Genesis. 38(1):39-50.

Gan L, Ye S, Chu A, Anton K, Yi S, Vincent VA, von Schack D, Chin D, Murray J, Lohr S et al.. 2004. Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach.. J Biol Chem. 279(7):5565-72.

Gan L, Ye S, Chu A, Anton K, Yi S, Vincent VA, von Schack D, Chin D, Murray J, Lohr S et al.. 2004. Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach.. J Biol Chem. 279(7):5565-72.

Esposito L, Gan L, Yu G-Q, Essrich C, Mucke L. 2004. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.. J Neurochem. 91(6):1260-74.

Gresch O, Engel FB, Nesic D, Tran TThai, England HM, Hickman ES, Körner I, Gan L, Chen S, Castro-Obregon S et al.. 2004. New non-viral method for gene transfer into primary cells.. Methods. 33(2):151-63.

Gresch O, Engel FB, Nesic D, Tran TThai, England HM, Hickman ES, Körner I, Gan L, Chen S, Castro-Obregon S et al.. 2004. New non-viral method for gene transfer into primary cells.. Methods. 33(2):151-63.

2003

Ford BD, Liu Y, Mann MAnne, Krauss R, Phillips K, Gan L, Fischbach GD. 2003. Neuregulin-1 suppresses muscarinic receptor expression and acetylcholine-activated muscarinic K+ channels in cardiac myocytes.. Biochem Biophys Res Commun. 308(1):23-8.

Zhou Y, Su Y, Li B, Liu F, Ryder JW, Wu X, Gonzalez-DeWhitt PA, Gelfanova V, Hale JE, May PC et al.. 2003. Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho.. Science. 302(5648):1215-7.

Zhou Y, Su Y, Li B, Liu F, Ryder JW, Wu X, Gonzalez-DeWhitt PA, Gelfanova V, Hale JE, May PC et al.. 2003. Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho.. Science. 302(5648):1215-7.

Benharouga M, Sharma M, So J, Haardt M, Drzymala L, Popov M, Schwapach B, Grinstein S, Du K, Lukacs GL. 2003. The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia.. J Biol Chem. 278(24):22079-89.

2002

Gong S, Yang XWilliam, Li C, Heintz N. 2002. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication.. Genome Res. 12(12):1992-8.

Dodart J-C, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM et al.. 2002. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.. Nat Neurosci. 5(5):452-7.

Dodart J-C, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM et al.. 2002. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.. Nat Neurosci. 5(5):452-7.

Bhattacharjee A, Gan L, Kaczmarek LK. 2002. Localization of the Slack potassium channel in the rat central nervous system.. J Comp Neurol. 454(3):241-54.

Gan L, Anton KE, Masterson BA, Vincent VAM, Ye S, Gonzalez-Zulueta M. 2002. Specific interference with gene expression and gene function mediated by long dsRNA in neural cells.. J Neurosci Methods. 121(2):151-7.

Gan L, Anton KE, Masterson BA, Vincent VAM, Ye S, Gonzalez-Zulueta M. 2002. Specific interference with gene expression and gene function mediated by long dsRNA in neural cells.. J Neurosci Methods. 121(2):151-7.

2001

Reichlin A, Hu Y, Meffre E, Nagaoka H, Gong S, Kraus M, Rajewsky K, Nussenzweig MC. 2001. B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta.. J Exp Med. 193(1):13-23.

Rho J, Gong S, Kim N, Choi Y. 2001. TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo.. Mol Cell Biol. 21(24):8365-70.

2000

Kronin V, Wu L, Gong S, Nussenzweig MC, Shortman K. 2000. DEC-205 as a marker of dendritic cells with regulatory effects on CD8 T cell responses.. Int Immunol. 12(5):731-5.