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Found 115 results
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2016
Tracy TE, Sohn PDongmin, S Minami S, Wang C, Min S-W, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R et al.
. 2016.
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
.
Neuron. 90(2):245-60.
Brand MD, Goncalves RLS, Orr AL, Vargas L, Gerencser AA, Jensen MBorch, Wang YT, Melov S, Turk CN, Matzen JT et al.
. 2016.
Suppressors of Superoxide-HO Production at Site I of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
.
Cell Metab. 24(4):582-592.
2015
Min S-W, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, S Minami S, Defensor E, Mok SAnn et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RLS et al.
. 2015.
Suppressors of superoxide production from mitochondrial complex III.
.
Nat Chem Biol. 11(11):834-6.
2014
Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M et al.
. 2014.
2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease.
.
Alzheimers Dement. 10(5 Suppl):S430-52.
Linsenbardt AJ, Taylor A, Emnett CM, Doherty JJ, Krishnan K, Covey DF, Paul SM, Zorumski CF, Mennerick S
. 2014.
Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.
.
Neuropharmacology. 85:232-42.
Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LHerl, Seeley WW et al.
. 2014.
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.
.
J Exp Med. 211(10):1937-45.
Strauss KA, Markx S, Georgi B, Paul SM, Jinks RN, Hoshi T, McDonald A, First MB, Liu W, Benkert AR et al.
. 2014.
A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder.
.
Hum Mol Genet. 23(23):6395-406.
2013
Grinberg LTenenholz, Wang X, Wang C, Sohn PDongmin, Theofilas P, Sidhu M, Arevalo JBenjamin, Heinsen H, Huang EJ, Rosen H et al.
. 2013.
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.
.
Acta Neuropathol. 125(4):581-93.
Edayathumangalam R, Wu R, Garcia R, Wang Y, Wang W, Kreinbring CA, Bach A, Liao J, Stone TA, Terwilliger TC et al.
. 2013.
Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.
.
Proc Natl Acad Sci U S A. 110(44):17820-5.
Liu CFeng, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D
. 2013.
A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.
.
Biochemistry. 52(9):1603-10.
2012
Quinlan CL, Orr AL, Perevoshchikova IV, Treberg JR, Ackrell BA, Brand MD
. 2012.
Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions.
.
J Biol Chem. 287(32):27255-64.
Quinlan CL, Treberg JR, Perevoshchikova IV, Orr AL, Brand MD
. 2012.
Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters.
.
Free Radic Biol Med. 53(9):1807-17.
2011
Etherton MR, Tabuchi K, Sharma M, Ko J, Südhof TC
. 2011.
An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.
.
EMBO J. 30(14):2908-19.
Witten IB, Steinberg EE, Lee SYeun, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C et al.
. 2011.
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement.
.
Neuron. 72(5):721-33.
Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH, Lindquist S et al.
. 2011.
A yeast model of FUS/TLS-dependent cytotoxicity.
.
PLoS Biol. 9(4):e1001052.
2010
Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC
. 2010.
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.
.
Science. 329(5999):1663-7.
Hurtado DE, Molina-Porcel L, Iba M, Aboagye AK, Paul SM, Trojanowski JQ, Lee VM-Y
. 2010.
A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.
.
Am J Pathol. 177(4):1977-88.
Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P et al.
. 2010.
Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists.
.
J Pharmacol Exp Ther. 333(3):650-62.
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RLA, Kim J, May J, Tocilescu MAleksandra, Liu W, Ko HSeok et al.
. 2010.
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
.
Proc Natl Acad Sci U S A. 107(1):378-83.
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RLA, Kim J, May J, Tocilescu MAleksandra, Liu W, Ko HSeok et al.
. 2010.
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
.
Proc Natl Acad Sci U S A. 107(1):378-83.
Mullasseril P, Hansen KB, Vance KM, Ogden KK, Yuan H, Kurtkaya NL, Santangelo R, Orr AG, Le P, Vellano KM et al.
. 2010.
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.
.
Nat Commun. 1:90.
2009
Orr AG, Orr AL, Li X-J, Gross RE, Traynelis SF
. 2009.
Adenosine A(2A) receptor mediates microglial process retraction.
.
Nat Neurosci. 12(7):872-8.
Gyoneva S, Orr AG, Traynelis SF
. 2009.
Differential regulation of microglial motility by ATP/ADP and adenosine.
.
Parkinsonism Relat Disord. 15 Suppl 3:S195-9.
Li Y, Liu W, Oo TF, Wang L, Tang Y, Jackson-Lewis V, Zhou C, Geghman K, Bogdanov M, Przedborski S et al.
. 2009.
Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease.
.
Nat Neurosci. 12(7):826-8.
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