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Found 19 results
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2023
Uekawa K
,
Hattori Y
,
Ahn SJi
,
Seo J
,
Casey N
,
Anfray A
,
Zhou P
,
Luo W
,
Anrather J
,
Park L
et al.
. 2023.
Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress.
.
Mol Neurodegener. 18(1):73.
2022
Dräger NM
,
Sattler SM
,
Huang CTzu-Ling
,
Teter OM
,
Leng K
,
Hashemi SHadi
,
Hong J
,
Aviles G
,
Clelland CD
,
Zhan L
et al.
. 2022.
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
.
Nat Neurosci.
2021
Xu P
,
Chang JC
,
Zhou X
,
Wang W
,
Bamkole M
,
Wong E
,
Bettayeb K
,
Jiang L-L
,
Huang T
,
Luo W
et al.
. 2021.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.
.
J Exp Med. 218(8)
2020
Inda MCarmen
,
Joshi S
,
Wang T
,
Bolaender A
,
Gandu S
,
Iii JKoren
,
Che AYue
,
Taldone T
,
Yan P
,
Sun W
et al.
. 2020.
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
.
Nat Commun. 11(1):319.
Inda MCarmen
,
Joshi S
,
Wang T
,
Bolaender A
,
Gandu S
,
Iii JKoren
,
Che AYue
,
Taldone T
,
Yan P
,
Sun W
et al.
. 2020.
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
.
Nat Commun. 11(1):319.
Luo W
,
Ip FCF
,
Fu G
,
Cheung K
,
Tian Y
,
Hu Y
,
Sinha A
,
Cheng EYL
,
Wu X
,
Bustos V
et al.
. 2020.
A Pentacyclic Triterpene from Targets γ-Secretase.
.
ACS Chem Neurosci. 11(18):2827-2835.
Luo W
,
Ip FCF
,
Fu G
,
Cheung K
,
Tian Y
,
Hu Y
,
Sinha A
,
Cheng EYL
,
Wu X
,
Bustos V
et al.
. 2020.
A Pentacyclic Triterpene from Targets γ-Secretase.
.
ACS Chem Neurosci. 11(18):2827-2835.
2019
Karch CM
,
Kao AW
,
Karydas A
,
Onanuga K
,
Martinez R
,
Argouarch A
,
Wang C
,
Huang C
,
Sohn PDongmin
,
Bowles KR
et al.
. 2019.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
.
Stem Cell Reports.
2018
Inoue K
,
Deng Z
,
Chen Y
,
Giannopoulou E
,
Xu R
,
Gong S
,
Greenblatt MB
,
Mangala LS
,
Lopez-Berestein G
,
Kirsch DG
et al.
. 2018.
Bone protection by inhibition of microRNA-182.
.
Nat Commun. 9(1):4108.
Sokhi UK
,
Liber MP
,
Frye L
,
Park S
,
Kang K
,
Pannellini T
,
Zhao B
,
Norinsky R
,
Ivashkiv LB
,
Gong S
. 2018.
Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.
.
Nat Commun. 9(1):658.
A Willsey J
,
Morris MT
,
Wang S
,
Willsey HR
,
Sun N
,
Teerikorpi N
,
Baum TB
,
Cagney G
,
Bender KJ
,
Desai TA
et al.
. 2018.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
.
Cell. 174(3):505-520.
2016
Faraco G
,
Park L
,
Zhou P
,
Luo W
,
Paul SM
,
Anrather J
,
Iadecola C
. 2016.
Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP.
.
J Cereb Blood Flow Metab. 36(1):241-52.
2013
Paul SM
,
Doherty JJ
,
Robichaud AJ
,
Belfort GM
,
Chow BY
,
Hammond RS
,
Crawford DC
,
Linsenbardt AJ
,
Shu H-J
,
Izumi Y
et al.
. 2013.
The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors.
.
J Neurosci. 33(44):17290-300.
Zorumski CF
,
Paul SM
,
Izumi Y
,
Covey DF
,
Mennerick S
. 2013.
Neurosteroids, stress and depression: potential therapeutic opportunities.
.
Neurosci Biobehav Rev. 37(1):109-22.
Qiao Y
,
Giannopoulou EG
,
Chan CHin
,
Park S-H
,
Gong S
,
Chen J
,
Hu X
,
Elemento O
,
Ivashkiv LB
. 2013.
Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.
.
Immunity. 39(3):454-69.
2010
Hurtado DE
,
Molina-Porcel L
,
Iba M
,
Aboagye AK
,
Paul SM
,
Trojanowski JQ
,
Lee VM-Y
. 2010.
A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.
.
Am J Pathol. 177(4):1977-88.
2005
Gu X
,
Li C
,
Wei W
,
Lo V
,
Gong S
,
Li S-H
,
Iwasato T
,
Itohara S
,
Li X-J
,
Mody I
et al.
. 2005.
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.
.
Neuron. 46(3):433-44.
Gu X
,
Li C
,
Wei W
,
Lo V
,
Gong S
,
Li S-H
,
Iwasato T
,
Itohara S
,
Li X-J
,
Mody I
et al.
. 2005.
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.
.
Neuron. 46(3):433-44.
1998
Ginns EI
,
St Jean P
,
Philibert RA
,
Galdzicka M
,
Damschroder-Williams P
,
Thiel B
,
Long RT
,
Ingraham LJ
,
Dalwaldi H
,
Murray MA
et al.
. 1998.
A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish.
.
Proc Natl Acad Sci U S A. 95(26):15531-6.