Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 410 results
[ Author(Desc)] Title Type Year
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Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R.  2013.  NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.. Neurosci Lett. 547:16-20.
Pranski EL, Dalal NV, Herskowitz JH, Orr AL, Roesch LA, Fritz JJ, Heilman C, Lah JJ, Levey AI, Betarbet RS.  2012.  Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling.. J Neuroinflammation. 9:67.
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Qiao Y, Giannopoulou EG, Chan CHin, Park S-H, Gong S, Chen J, Hu X, Elemento O, Ivashkiv LB.  2013.  Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.. Immunity. 39(3):454-69.
Quinlan CL, Perevoshchikova IV, Hey-Mogensen M, Orr AL, Brand MD.  2013.  Sites of reactive oxygen species generation by mitochondria oxidizing different substrates.. Redox Biol. 1:304-12.
Quinlan CL, Treberg JR, Perevoshchikova IV, Orr AL, Brand MD.  2012.  Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters.. Free Radic Biol Med. 53(9):1807-17.
Quinlan CL, Orr AL, Perevoshchikova IV, Treberg JR, Ackrell BA, Brand MD.  2012.  Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions.. J Biol Chem. 287(32):27255-64.
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Ray SD, Parmar M, Syed I, Rathod J, Zinkovsky D, Bulku E, Gigliotti J, Hackman RM, Stohs SJ.  2008.  Long term exposure effect of a unique metabolic nutrition system containing a diverse group of phytochemicals on serum chemistry and genomic and non-genomic changes in the liver of female B6C3F1 mice.. Phytother Res. 22(4):458-71.
Reichlin A, Hu Y, Meffre E, Nagaoka H, Gong S, Kraus M, Rajewsky K, Nussenzweig MC.  2001.  B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta.. J Exp Med. 193(1):13-23.
Rho J, Gong S, Kim N, Choi Y.  2001.  TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo.. Mol Cell Biol. 21(24):8365-70.
Ringe D, Petsko GA.  2009.  What are pharmacological chaperones and why are they interesting? J Biol. 8(9):80.
Rodriguez-Rodriguez P, Arroyo-Garcia LEnrique, Tsagkogianni C, Li L, Wang W, Végvári Á, Salas-Allende I, Plautz Z, Cedazo-Minguez A, Sinha SC et al..  2024.  A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.. Brain. 147(7):2384-2399.
Rohan ML, Yamamoto RT, Ravichandran CT, Cayetano KR, Morales OG, Olson DP, Vitaliano G, Paul SM, Cohen BM.  2014.  Rapid mood-elevating effects of low field magnetic stimulation in depression.. Biol Psychiatry. 76(3):186-93.
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Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CParra, Goodness D, Tian R, Grosjean P, Abskharon R, Eisenberg D et al..  2023.  CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.. bioRxiv.
Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu G-Q, Palop JJ et al..  2012.  Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.. Proc Natl Acad Sci U S A. 109(42):E2895-903.
Sanchez-Mejia RO, Newman JW, Toh S, Yu G-Q, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L et al..  2008.  Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.. Nat Neurosci. 11(11):1311-8.
Sang T-K, Li C, Liu W, Rodriguez A, Abrams JM, S Zipursky L, Jackson GR.  2005.  Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis.. Hum Mol Genet. 14(3):357-72.
Saura J, Petegnief V, Wu X, Liang Y, Paul SM.  2003.  Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide.. J Neurochem. 85(6):1455-67.
Sayed FA, Kodama L, Fan L, Carling GK, Udeochu JC, Le D, Li Q, Zhou L, Wong MYing, Horowitz R et al..  2021.  AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.. Sci Transl Med. 13(622):eabe3947.
Sayed FA, Telpoukhovskaia M, Kodama L, Li Y, Zhou Y, Le D, Hauduc A, Ludwig C, Gao F, Clelland C et al..  2018.  Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.. Proc Natl Acad Sci U S A. 115(40):10172-10177.
Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG.  2000.  The catalytic pathway of cytochrome p450cam at atomic resolution.. Science. 287(5458):1615-22.
Schmidt EF, Kus L, Gong S, Heintz N.  2013.  BAC transgenic mice and the GENSAT database of engineered mouse strains.. Cold Spring Harb Protoc. 2013(3)
Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MBukar, Clelland CD, Cohen AD, Crary JF, Dage JL et al..  2024.  Novel avenues of tau research.. Alzheimers Dement.
Sha SJ, Miller ZA, Min S-W, Zhou Y, Brown J, Mitic LL, Karydas A, Koestler M, Tsai R, Corbetta-Rastelli C et al..  2017.  An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from gene mutations.. Alzheimers Dement (N Y). 3(4):507-512.
Sharma M, Burré J.  2023.  α-Synuclein in synaptic function and dysfunction.. Trends Neurosci. 46(2):153-166.
Sharma M, Benharouga M, Hu W, Lukacs GL.  2001.  Conformational and temperature-sensitive stability defects of the delta F508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments.. J Biol Chem. 276(12):8942-50.