Helen & Robert Appel Alzheimer’s Disease Research Institute

Publications

Found 32 results
Author Title Type [ Year(Desc)]
Filters: Author is Burré, Jacqueline  [Clear All Filters]
2005
Morciano M, Burré J, Corvey C, Karas M, Zimmermann H, Volknandt W.  2005.  Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis.. J Neurochem. 95(6):1732-45.
2006
Burré J, Beckhaus T, Schägger H, Corvey C, Hofmann S, Karas M, Zimmermann H, Volknandt W.  2006.  Analysis of the synaptic vesicle proteome using three gel-based protein separation techniques.. Proteomics. 6(23):6250-62.
Burré J, Beckhaus T, Corvey C, Karas M, Zimmermann H, Volknandt W.  2006.  Synaptic vesicle proteins under conditions of rest and activation: analysis by 2-D difference gel electrophoresis.. Electrophoresis. 27(17):3488-96.
2007
Burré J, Zimmermann H, Volknandt W.  2007.  Identification and characterization of SV31, a novel synaptic vesicle membrane protein and potential transporter.. J Neurochem. 103(1):276-87.
Burré J, Zimmermann H, Volknandt W.  2007.  Immunoisolation and subfractionation of synaptic vesicle proteins.. Anal Biochem. 362(2):172-81.
Burré J, Volknandt W.  2007.  The synaptic vesicle proteome.. J Neurochem. 101(6):1448-62.
2009
Burré J, Wittig I, Schägger H.  2009.  Non-classical 2-D electrophoresis.. Methods Mol Biol. 564:33-57.
2010
Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC.  2010.  Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.. Science. 329(5999):1663-7.
2011
Sharma M, Burré J, Südhof TC.  2011.  CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.. Nat Cell Biol. 13(1):30-9.
2012
Sharma M, Burré J, Bronk P, Zhang Y, Xu W, Südhof TC.  2012.  CSPα knockout causes neurodegeneration by impairing SNAP-25 function.. EMBO J. 31(4):829-41.
Sharma M, Burré J, Südhof TC.  2012.  Proteasome inhibition alleviates SNARE-dependent neurodegeneration.. Sci Transl Med. 4(147):147ra113.
Burré J, Sharma M, Südhof TC.  2012.  Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities.. J Neurosci. 32(43):15227-42.
2013
Diao J, Burré J, Vivona S, Cipriano DJ, Sharma M, Kyoung M, Südhof TC, Brunger AT.  2013.  Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2.. Elife. 2:e00592.
Burré J, Vivona S, Diao J, Sharma M, Brunger AT, Südhof TC.  2013.  Properties of native brain α-synuclein.. Nature. 498(7453):E4-6;discussionE6-7.
2014
Acuna C, Guo Q, Burré J, Sharma M, Sun J, Südhof TC.  2014.  Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity.. Neuron. 82(5):1088-100.
Burré J, Sharma M, Südhof TC.  2014.  α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation.. Proc Natl Acad Sci U S A. 111(40):E4274-83.
2015
Burré J, Sharma M, Südhof TC.  2015.  Definition of a molecular pathway mediating α-synuclein neurotoxicity.. J Neurosci. 35(13):5221-32.
Burré J.  2015.  The Synaptic Function of α-Synuclein.. J Parkinsons Dis. 5(4):699-713.
Bacaj T, Wu D, Burré J, Malenka RC, Liu X, Südhof TC.  2015.  Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles.. PLoS Biol. 13(10):e1002267.
2017
Pineda A, Burré J.  2017.  Modulating membrane binding of α-synuclein as a therapeutic strategy.. Proc Natl Acad Sci U S A. 114(6):1223-1225.
2018
Burré J, Sharma M, Südhof TC.  2018.  Cell Biology and Pathophysiology of α-Synuclein.. Cold Spring Harb Perspect Med. 8(3)
Guiberson NGuy Lewis, Pineda A, Abramov D, Kharel P, Carnazza KE, Wragg RT, Dittman JS, Burré J.  2018.  Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.. Nat Commun. 9(1):3986.
2020
Naseri NN, Ergel B, Kharel P, Na Y, Huang Q, Huang R, Dolzhanskaya N, Burré J, Velinov MT, Sharma M.  2020.  Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.. Nat Struct Mol Biol. 27(2):192-201.
Abramov D, Guiberson NGuy Lewis, Burré J.  2020.  STXBP1 encephalopathies: Clinical spectrum, disease mechanisms, and therapeutic strategies.. J Neurochem.
Abramov D, Guiberson NGuy Lewis, Daab A, Na Y, Petsko GA, Sharma M, Burré J.  2020.  Targeted stabilization of Munc18-1 function via pharmacological chaperones.. EMBO Mol Med. :e12354.