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Found 15 results
Author
Title
Type
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Year
]
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Author
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Li, Yaqiao
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2024
Bravo CParra
,
Krukowski K
,
Barker S
,
Wang C
,
Li Y
,
Fan L
,
Vázquez-Rosa E
,
Shin M-K
,
Wong MYing
,
McCullough LD
et al.
. 2024.
Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
.
Mol Neurodegener. 19(1):51.
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2024.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
J Clin Invest. 134(3)
2023
Kauwe G
,
Pareja-Navarro KA
,
Yao L
,
Chen JH
,
Wong I
,
Saloner R
,
Cifuentes H
,
Nana AL
,
Shah S
,
Li Y
et al.
. 2023.
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.
.
bioRxiv.
2022
Wang C
,
Fan L
,
Khawaja RR
,
Liu B
,
Zhan L
,
Kodama L
,
Chin M
,
Li Y
,
Le D
,
Zhou Y
et al.
. 2022.
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
.
Nat Commun. 13(1):1969.
2021
Sayed FA
,
Kodama L
,
Fan L
,
Carling GK
,
Udeochu JC
,
Le D
,
Li Q
,
Zhou L
,
Wong MYing
,
Horowitz R
et al.
. 2021.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
.
Sci Transl Med. 13(622):eabe3947.
2020
Telpoukhovskaia MA
,
Liu K
,
Sayed FA
,
Etchegaray JIker
,
Xie M
,
Zhan L
,
Li Y
,
Zhou Y
,
Le D
,
Bahr BA
et al.
. 2020.
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.
.
Sci Rep. 10(1):13688.
Zhan L
,
Fan L
,
Kodama L
,
Sohn PDongmin
,
Wong MYing
,
Mousa GAlzaem
,
Zhou Y
,
Li Y
,
Gan L
. 2020.
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.
.
Elife. 9
Chen X
,
Li Y
,
Wang C
,
Tang Y
,
Mok S-A
,
Tsai RM
,
Rojas JC
,
Karydas A
,
Miller BL
,
Boxer AL
et al.
. 2020.
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.
.
Mol Neurodegener. 15(1):2.
2019
Kodama L
,
Guzman E
,
Etchegaray JI
,
Li Y
,
Sayed FA
,
Zhou L
,
Zhou Y
,
Zhan L
,
Le D
,
Udeochu JC
et al.
. 2019.
Microglial microRNAs mediate sex-specific responses to tau pathology.
.
Nat Neurosci.
Zhan L
,
Krabbe G
,
Du F
,
Jones I
,
Reichert MC
,
Telpoukhovskaia M
,
Kodama L
,
Wang C
,
Cho S-H
,
Sayed F
et al.
. 2019.
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.
.
PLoS Biol. 17(2):e3000134.
2018
Sayed FA
,
Telpoukhovskaia M
,
Kodama L
,
Li Y
,
Zhou Y
,
Le D
,
Hauduc A
,
Ludwig C
,
Gao F
,
Clelland C
et al.
. 2018.
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
.
Proc Natl Acad Sci U S A. 115(40):10172-10177.
Min S-W
,
Sohn PDongmin
,
Li Y
,
Devidze N
,
Johnson JR
,
Krogan NJ
,
Masliah E
,
Mok S-A
,
Gestwicki JE
,
Gan L
. 2018.
SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.
.
J Neurosci. 38(15):3680-3688.
2016
Tracy TE
,
Sohn PDongmin
,
S Minami S
,
Wang C
,
Min S-W
,
Li Y
,
Zhou Y
,
Le D
,
Lo I
,
Ponnusamy R
et al.
. 2016.
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
.
Neuron. 90(2):245-60.
2015
Min S-W
,
Chen X
,
Tracy TE
,
Li Y
,
Zhou Y
,
Wang C
,
Shirakawa K
,
S Minami S
,
Defensor E
,
Mok SAnn
et al.
. 2015.
Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
.
Nat Med. 21(10):1154-62.
2014
S Minami S
,
Min S-W
,
Krabbe G
,
Wang C
,
Zhou Y
,
Asgarov R
,
Li Y
,
Martens LH
,
Elia LP
,
Ward ME
et al.
. 2014.
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.
.
Nat Med. 20(10):1157-64.