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Brand, Martin D
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Orr AL
,
Ashok D
,
Sarantos MR
,
Shi T
,
Hughes RE
,
Brand MD
. 2013.
Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening.
.
Free Radic Biol Med. 65:1047-1059.
M
Quinlan CL
,
Orr AL
,
Perevoshchikova IV
,
Treberg JR
,
Ackrell BA
,
Brand MD
. 2012.
Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions.
.
J Biol Chem. 287(32):27255-64.
N
Quinlan CL
,
Treberg JR
,
Perevoshchikova IV
,
Orr AL
,
Brand MD
. 2012.
Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters.
.
Free Radic Biol Med. 53(9):1807-17.
Orr AL
,
Ashok D
,
Sarantos MR
,
Ng R
,
Shi T
,
Gerencser AA
,
Hughes RE
,
Brand MD
. 2014.
Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.
.
PLoS One. 9(2):e89938.
P
Wong H-S
,
Monternier P-A
,
Orr AL
,
Brand MD
. 2018.
Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria.
.
Methods Mol Biol. 1782:287-299.
Hey-Mogensen M
,
Goncalves RLS
,
Orr AL
,
Brand MD
. 2014.
Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria.
.
Free Radic Biol Med. 72:149-55.
R
Birket MJ
,
Orr AL
,
Gerencser AA
,
Madden DT
,
Vitelli C
,
Swistowski A
,
Brand MD
,
Zeng X
. 2011.
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.
.
J Cell Sci. 124(Pt 3):348-58.
Orr AL
,
Quinlan CL
,
Perevoshchikova IV
,
Brand MD
. 2012.
A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase.
.
J Biol Chem. 287(51):42921-35.
S
Quinlan CL
,
Perevoshchikova IV
,
Hey-Mogensen M
,
Orr AL
,
Brand MD
. 2013.
Sites of reactive oxygen species generation by mitochondria oxidizing different substrates.
.
Redox Biol. 1:304-12.
Perevoshchikova IV
,
Quinlan CL
,
Orr AL
,
Gerencser AA
,
Brand MD
. 2013.
Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria.
.
Free Radic Biol Med. 61:298-309.
Orr AL
,
Vargas L
,
Turk CN
,
Baaten JE
,
Matzen JT
,
Dardov VJ
,
Attle SJ
,
Li J
,
Quackenbush DC
,
Goncalves RLS
et al.
. 2015.
Suppressors of superoxide production from mitochondrial complex III.
.
Nat Chem Biol. 11(11):834-6.
Brand MD
,
Goncalves RLS
,
Orr AL
,
Vargas L
,
Gerencser AA
,
Jensen MBorch
,
Wang YT
,
Melov S
,
Turk CN
,
Matzen JT
et al.
. 2016.
Suppressors of Superoxide-HO Production at Site I of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
.
Cell Metab. 24(4):582-592.